Results 41 to 50 of about 196,719 (315)
The collective lie in ketamine therapy: a call to realign clinical practice with neurobiology
Frontiers in PsychiatryIn recent years, ketamine therapy has become increasingly entangled with psychedelic culture, leading to widespread misinterpretation of its therapeutic mechanism.
Charles Miller +2 more
doaj +1 more source
Considerations for physicians using ketamine for sedation of children in emergency departments [PDF]
Clinical and Experimental Emergency Medicine, 2017 Objective Ketamine use in emergency departments (EDs) for procedural sedation and analgesia is becoming increasingly common. However, few studies have examined patient factors related to adverse events associated with ketamine.
Woo Sung Kim +5 more
doaj +1 more source
European Journal of PsychotraumatologyBackground: Posttraumatic stress disorder (PTSD) is associated with maladaptive memory reconsolidation and overgeneralized fear responses. EMDR therapy promotes trauma reprocessing by activating the brain’s intrinsic memory reconsolidation mechanism ...
Michele Topel, Danielle Ciccone
doaj +1 more source
Biosensors Show the Pharmacokinetics of S-Ketamine in the Endoplasmic Reticulum
Frontiers in Cellular Neuroscience, 2019 The target for the “rapid” (<24 h) antidepressant effects of S-ketamine is unknown, vitiating programs to rationally develop more effective rapid antidepressants.
Kallol Bera +19 more
doaj +1 more source
Mis-anaesthetized society: expectancies and recreational use of ketamine in Taiwan
BMC Public Health, 2019 Background The popularity of ketamine for recreational use has been increasing in Asia, including Taiwan. Still, little known about the pattern of ketamine expectancies and whether such patterns are related to ketamine use.
Chao-Ming Chang +5 more
doaj +1 more source
Translational Psychiatry, 2021 Intravenous (IV) subanesthetic doses of ketamine have been shown to reduce psychiatric distress in both major depressive (MDD) and posttraumatic stress disorder (PTSD).
Margaret T. Davis +4 more
doaj +1 more source
Journal of Neuroinflammation, 2022 Background Ketamine, a multimodal dissociative anesthetic drug, is widely used as an analgesic following traumatic injury. Although ketamine may produce anti-inflammatory effects when administered after injury, the immunomodulatory properties of ...
Haley F. Spencer +6 more
doaj +1 more source
Understanding mechanisms of Ketamine-induced human urinary tract damage [PDF]
, 2011 Ketamine is a phencyclidine derivative N-Methyl D-Aspartate (NMDA) receptor antagonist used as an anaesthetic and analgesic. A florid non-bacterial cystitis condition known as ketamine-induced cystitis (KIC) has recently been reported in abusers and ...
Shahzad, Khurram
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source