Results 21 to 30 of about 196,719 (315)

Sleep quality among individuals with ketamine use and the mediating role of craving

Scientific Reports, 2020
Sleep problems are common in Taiwan. Poor sleep may be associated with many illnesses, including substance use disorders. Ketamine use disorder has significantly increased in Taiwan in recent years and may lead to physical and cognitive problems. Craving
Cheng-Fang Yen, Huang-Chi Lin, Chih-Hung Ko, Hung-Chi Wu, Chih-Yao Hsu, Peng-Wei Wang   +5 more
doaj   +1 more source

Determination of Diffusion Kinetics of Ketamine in Brain Tissue: Implications for in vitro Mechanistic Studies of Drug Actions

Frontiers in Neuroscience, 2021
Ketamine has been in use for over 50 years as a general anesthetic, acting primarily through blockade of N-methyl-D-aspartate receptors in the brain. Recent studies have demonstrated that ketamine also acts as a potent and rapid-acting antidepressant ...
Zachary Geiger, Brett VanVeller, Zarin Lopez, Abdel K. Harrata, Kathryn Battani, Lauren Wegman-Points, Li-Lian Yuan   +6 more
doaj   +1 more source

Ketamine for pain [PDF]

F1000Research, 2017
The efficacy of theN-methyl-D-aspartate receptor antagonist ketamine as an analgesic agent is still under debate, especially for indications such as chronic pain. To understand the efficacy of ketamine for relief of pain, we performed a literature search for relevant narrative and systematic reviews and meta-analyses.
Kelly Jonkman, Albert Dahan, Tine van de Donk, Leon Aarts, Marieke Niesters, Monique van Velzen   +5 more
openaire   +2 more sources

Ketamine infusion as a sedative-analgesic in severe ARDS (KISS)

Journal of Community Hospital Internal Medicine Perspectives, 2021
Rationale Ketamine has been used as a sedative analgesic in trauma setting, but data regarding its efficacy and safety is lacking in severe ARDS.
Ramakanth Pata, Pagali Sandeep, Htun Min Aung, Meet J Patel, Tsering Dolkar, Nway Nway, Kosuru Bhanu, Abolfazl Ahmady, Roudabeh Kiani, Ramaiah Swaroop, Frances Schmidt, Danilo Enriquez   +11 more
doaj   +1 more source

A survey of drug liking and cravings in patients using sublingual or intranasal ketamine for treatment resistant depression: A preliminary evaluation of real world addictive potential

Frontiers in Psychiatry, 2022
Ketamine has gained rapid popularity as a treatment option for treatment resistant depression (TRD). Though seen only in limited contexts, ketamine is a potential drug of abuse, addiction and diversion.
Brittany Chubbs, Jay Wang, Shaina Archer, Carson Chrenek, Atul Khullar, Michael Wolowyk, Jennifer Swainson   +6 more
doaj   +1 more source

Ketamine administration in healthy volunteers reproduces aberrant agency experiences associated with schizophrenia [PDF]

, 2011
Introduction. Aberrant experience of agency is characteristic of schizophrenia. An understanding of the neurobiological basis of such experience is therefore of considerable importance for developing successful models of the disease.
Everitt, J.C., Pigott, J.S., Moore, J.W., Gardner, Jenny M., Pigott, Jennifer S., Morgan, Hannah L., Arana, F.S., Fernando S. Arana, Moore, James W., Arana, Fernando S., Adapa, Ram, Philip R. Corlett, de Wit, Sanne, Patrick Haggard, Danielle C. Turner, Haggard, Patrick, Fletcher, Paul C., Jennifer S. Pigott, Adapa, R., Jessica C. Everitt, Everitt, Jessica C., de Wit, S.; id_orcid, de Wit, S., Gardner, J.M., Hannah L. Morgan, Absalom, A.R., Antony R. Absalom, Morgan, H.L., Haggard, P., Paul C. Fletcher, Corlett, Philip R., James W. Moore, Ram Adapa, Corlett, P.R., Jenny M. Gardner, Turner, D.C., Sanne de Wit, Fletcher, P.C., Absalom, Antony R.; id_orcid, Turner, Danielle C., Absalom, Antony R.   +40 more
core   +1 more source

Prolonged ketamine infusion as a therapy for complex regional pain syndrome:Synergism with antagonism? [PDF]

, 2014
Complex regional pain syndrome (CRPS) remains a troubling and often refractory pain condition for which the existing treatments are inadequate. The review by Niesters et al in this journal highlights the interesting findings of several recent studies of ...
McCabe, Candy, Pickering, Anthony E., McCabe, Candida S.   +2 more
core   +1 more source

'Special K' and a loss of cell-to-cell adhesion in proximal tubule-derived epithelial cells : modulation of the adherens junction complex by ketamine [PDF]

, 2013
Ketamine, a mild hallucinogenic class C drug, is the fastest growing ‘party drug’ used by 16–24 year olds in the UK. As the recreational use of Ketamine increases we are beginning to see the signs of major renal and bladder complications. To date however,
Claire E Hills, Hills Claire E., Jefferson Kieran P., Squires, Paul E., Issac K-K Liu, Tianrong Jin (452021), Jefferson, Kieran P., Liu, Kuo-Kang, Siamantouras Eleftherios, Siamantouras, Eleftherios, Claire E. Hills (452020), Hills, Claire E., Jin, Tianrong, Eleftherios Siamantouras, Paul E. Squires (452025), Jin Tianrong, Issac K-K Liu (452023), Squires Paul E., Tianrong Jin, Paul E Squires, Liu Issac K-K, Kieran P Jefferson, Kieran P. Jefferson (452024), Eleftherios Siamantouras (452022)   +23 more
core   +1 more source

Cortical Thickness Changes in Chronic Ketamine Users

Frontiers in Psychiatry, 2021
Background: Previous studies have examined the effects of long-term ketamine use on gray matter volume. But it is unclear whether chronic ketamine use alters cortical thickness and whether cortical thickness changes in chronic ketamine users are ...
Jun Zhong, Huawang Wu, Fengchun Wu, Hongbo He, Zhaohua Zhang, Jiaxin Huang, Penghui Cao, Ni Fan   +7 more
doaj   +1 more source

Time, action and psychosis: using subjective time to investigate the effects of ketamine on sense of agency [PDF]

, 2012
Sense of agency refers to the experience of initiating and controlling actions in order to influence events in the outside world. A disturbed sense of agency is found in certain psychiatric and neurological disorders, most notably schizophrenia. Sense of
GIORLANDO, FRANCESCO, Adapa, R., Moore, J.W., Cambridge, V.C., Morgan, H., MOORE, JW, Moore, James W., Fletcher, PC, Fletcher, P.C., Adapa, R, Morgan, H, Cambridge, VC, Giorlando, F, Giorlando, F.   +13 more
core   +1 more source