Results 21 to 30 of about 276,611 (294)
Cortical Thickness Changes in Chronic Ketamine Users
Frontiers in Psychiatry, 2021 Background: Previous studies have examined the effects of long-term ketamine use on gray matter volume. But it is unclear whether chronic ketamine use alters cortical thickness and whether cortical thickness changes in chronic ketamine users are ...
Jun Zhong +7 more
doaj +1 more source
Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. [PDF]
, 2015 BackgroundKetamine produces schizophrenia-like behavioral phenotypes in healthy people. Prolonged ketamine effects and exacerbation of symptoms after the administration of ketamine have been observed in patients with schizophrenia.
Buell, Mahalah R +7 more
core +1 more source
Cellular Physiology and Biochemistry, 2014 Background: Recent animal experiments have suggested that ketamine administration during development might induce widespread neurodegeneration and long-term cognitive deficits. The underlying mechanism is not fully understood.
Jia Yan +4 more
doaj +1 more source
Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications. [PDF]
, 2017 Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of ...
Abagyan, Ruben +3 more
core +2 more sources
PLoS ONE, 2022 PurposeTo assess the effect of continuous ketamine administration in patients admitted to medical and cardiac intensive care units (ICUs) and received mechanical ventilation support.MethodsWe conducted a retrospective cohort study between March 2012 and ...
Hohyung Jung +6 more
doaj +1 more source
Frontiers in Psychiatry, 2022 Intravenous and intranasal ketamine have been shown to be effective therapeutic options in patients suffering from treatment-resistant depression (TRD).
Kazi Hassan +3 more
doaj +1 more source
Ketamine: NMDA receptors and beyond [PDF]
, 2016 Human studies examining the effects of the dissociative anesthetic ketamine as a model for psychosis and as a rapidly acting antidepressant have spurred great interest in understanding ketamine's actions at molecular, cellular, and network levels ...
Izumi, Yukitoshi +2 more
core +2 more sources
Safety and efficacy of a propofol and ketamine based procedural sedation protocol in children with cerebral palsy undergoing botulinum toxin A injections. [PDF]
, 2019 Background Pediatric patients with cerebral palsy (CP) often undergo intramuscular botulinum toxin (BoNT‐A) injections. These injections can be painful and may require procedural sedation.
Abu-Sultaneh, Samer +4 more
core +1 more source
Prenatal ketamine exposure causes abnormal development of prefrontal cortex in rat. [PDF]
, 2016 Ketamine is commonly used for anesthesia and as a recreational drug. In pregnant users, a potential neurotoxicity in offspring has been noted. Our previous work demonstrated that ketamine exposure of pregnant rats induces affective disorders and ...
Li, C +6 more
core +1 more source
Administration of Nebulized Ketamine for Managing Acute Pain in the Emergency Department: A Case Series [PDF]
, 2020 Ketamine administration in sub-dissociative doses in the emergency department (ED) results in effective pain relief in patients with acute traumatic and non-traumatic pain, chronic pain, and opioid-tolerant pain.
Butt, Mahlaqa +5 more
core