Results 21 to 30 of about 219,641 (298)
Cortical Thickness Changes in Chronic Ketamine Users
Frontiers in Psychiatry, 2021 Background: Previous studies have examined the effects of long-term ketamine use on gray matter volume. But it is unclear whether chronic ketamine use alters cortical thickness and whether cortical thickness changes in chronic ketamine users are ...
Jun Zhong +7 more
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British Journal of Anaesthesia, 2018 The file associated with this record is under embargo until 12 months after publication, in accordance with the publisher's self-archiving policy. The full text may be available through the publisher links provided above. ; Since Domino and colleagues reported the first clinical use of ketamine more than half a century ago there have been many clinical
Hirota, K, Lambert, DG
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'Special K' and a loss of cell-to-cell adhesion in proximal tubule-derived epithelial cells : modulation of the adherens junction complex by ketamine [PDF]
, 2013 Ketamine, a mild hallucinogenic class C drug, is the fastest growing ‘party drug’ used by 16–24 year olds in the UK. As the recreational use of Ketamine increases we are beginning to see the signs of major renal and bladder complications. To date however,
Claire E Hills +23 more
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Translational Psychiatry, 2021 Intravenous (IV) subanesthetic doses of ketamine have been shown to reduce psychiatric distress in both major depressive (MDD) and posttraumatic stress disorder (PTSD).
Margaret T. Davis +4 more
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Frontiers in Neuroscience, 2021 Ketamine has been in use for over 50 years as a general anesthetic, acting primarily through blockade of N-methyl-D-aspartate receptors in the brain. Recent studies have demonstrated that ketamine also acts as a potent and rapid-acting antidepressant ...
Zachary Geiger +6 more
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Application of Ketamine in Pain Management and the Underlying Mechanism
Pain Research and Management, 2023 Since ketamine was approved by the FDA as an intravenous anesthetic, it has been in clinical use for more than 50 years. Apart from its anesthetic effects, ketamine is one of the few intravenous anesthetics with potent analgesic properties.
Xiaofan Ma, Jia Yan, Hong Jiang
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Cellular Physiology and Biochemistry, 2014 Background: Recent animal experiments have suggested that ketamine administration during development might induce widespread neurodegeneration and long-term cognitive deficits. The underlying mechanism is not fully understood.
Jia Yan +4 more
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A review on the recent application of ketamine in management of anesthesia, pain, and health care
Journal of Family Medicine and Primary Care, 2020 Ketamine is considered as a promising drug for many clinical applications even after five decades since its discovery. Ketamine is a dissociative anesthetic agent with a variety of pharmacological effects from anesthetic induction and maintenance to ...
Abolfazl Abdollahpour +2 more
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The collective lie in ketamine therapy: a call to realign clinical practice with neurobiology
Frontiers in PsychiatryIn recent years, ketamine therapy has become increasingly entangled with psychedelic culture, leading to widespread misinterpretation of its therapeutic mechanism.
Charles Miller +2 more
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Frontiers in Psychiatry, 2022 Ketamine has gained rapid popularity as a treatment option for treatment resistant depression (TRD). Though seen only in limited contexts, ketamine is a potential drug of abuse, addiction and diversion.
Brittany Chubbs +6 more
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