Mis-anaesthetized society: expectancies and recreational use of ketamine in Taiwan
BMC Public Health, 2019 Background The popularity of ketamine for recreational use has been increasing in Asia, including Taiwan. Still, little known about the pattern of ketamine expectancies and whether such patterns are related to ketamine use.
Chao-Ming Chang +5 more
doaj +1 more source
Frontiers in Psychiatry, 2022 Ketamine has gained rapid popularity as a treatment option for treatment resistant depression (TRD). Though seen only in limited contexts, ketamine is a potential drug of abuse, addiction and diversion.
Brittany Chubbs +6 more
doaj +1 more source
Postnatal functional inactivation of the ventral subiculum enhances dopaminergic responses in the core part of the nucleus accumbens following ketamine injection in adult rats [PDF]
, 2020 For almost two decades schizophrenia has been considered to be a functional disconnection disorder. This functional disconnectivity between several brain regions could have a neurodevelopmental origin. Various approaches suggest the ventral subiculum (SUB) is a particular target region for neurodevelopemental disturbances in schizophrenia.
arxiv +1 more source
Cerebral and cardiovascular effects of analgesic doses of ketamine during a target controlled general anesthesia: a prospective randomized study [PDF]
, 2017 Introduction: Ketamine is increasingly being used in various pain settings. The purpose of this study was to assess the effect of an analgesic dose of ketamine in the bispectral index (BIS), spectral edge frequency (SEF-95), density spectral array (DSA),
Araujo, A. M. +3 more
core +1 more source
Ketamine administration in healthy volunteers reproduces aberrant agency experiences associated with schizophrenia [PDF]
, 2011 Introduction. Aberrant experience of agency is characteristic of schizophrenia. An understanding of the neurobiological basis of such experience is therefore of considerable importance for developing successful models of the disease.
Absalom, Antony R. +12 more
core +2 more sources
The efficacy and safety of ketamine for depression in patients with cancer: A systematic review [PDF]
, 2023 Management of depression in the oncology population includes supportive psychotherapeutic interventions with or without psychotropic medication, which take time to demonstrate effectiveness.
Azari, Leila +10 more
core +1 more source
Activation of σ1-Receptors by R-Ketamine May Enhance the Antidepressant Effect of S-Ketamine
Biomedicines, 2023 Ketamine is a racemic mixture composed of two enantiomers, S-ketamine and R-ketamine. In preclinical studies, both enantiomers have exhibited antidepressant effects, but these effects are attributed to distinct pharmacological activities.
Hans O. Kalkman
doaj +1 more source
Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications. [PDF]
, 2017 Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of ...
Abagyan, Ruben +3 more
core +2 more sources
Is approving esketamine as an antidepressant for treatment resistant depression associated with recreational use and risk perception of ketamine? Results from a longitudinal and cross-sectional survey in nightlife attendees [PDF]
, 2022 Background Esketamine was licensed for use in treatment resistant depression by the European Medicines Agency in December 2019. It is unclear whether this new approval has lowered the risk perception of recreational ketamine use.
Curran, H. Valerie +4 more
core +2 more sources
S-ketamine and intranasal application: alternatives for the castration of male suckling piglets?
BMC Veterinary Research, 2021 Background The intramuscular injection of ketamine and azaperone was proposed as a suitable anaesthesia for male suckling piglets for surgical castration.
Sabrina Becker +4 more
doaj +1 more source