Results 31 to 40 of about 290,727 (340)

Biosensors Show the Pharmacokinetics of S-Ketamine in the Endoplasmic Reticulum

Frontiers in Cellular Neuroscience, 2019
The target for the “rapid” (<24 h) antidepressant effects of S-ketamine is unknown, vitiating programs to rationally develop more effective rapid antidepressants.
Kallol Bera, Aron Kamajaya, Amol V. Shivange, Anand K. Muthusamy, Anand K. Muthusamy, Aaron L. Nichols, Aaron L. Nichols, Philip M. Borden, Stephen Grant, Janice Jeon, Elaine Lin, Ishak Bishara, Theodore M. Chin, Bruce N. Cohen, Charlene H. Kim, Elizabeth K. Unger, Lin Tian, Jonathan S. Marvin, Loren L. Looger, Henry A. Lester   +19 more
doaj   +1 more source

Safety and feasibility of continuous ketamine infusion for analgosedation in medical and cardiac ICU patients who received mechanical ventilation support: A retrospective cohort study.

PLoS ONE, 2022
PurposeTo assess the effect of continuous ketamine administration in patients admitted to medical and cardiac intensive care units (ICUs) and received mechanical ventilation support.MethodsWe conducted a retrospective cohort study between March 2012 and ...
Hohyung Jung, Jihye Lee, Hyun Young Ahn, Jeong Hoon Yang, Gee Young Suh, Ryoung-Eun Ko, Chi Ryang Chung   +6 more
doaj   +1 more source

Safety and efficacy of a propofol and ketamine based procedural sedation protocol in children with cerebral palsy undergoing botulinum toxin A injections. [PDF]

, 2019
Background Pediatric patients with cerebral palsy (CP) often undergo intramuscular botulinum toxin (BoNT‐A) injections. These injections can be painful and may require procedural sedation.
Abu-Sultaneh, Samer, Abulebda, Kamal, Louer, Ryan, Lutfi, Riad, McKinney, Renee C.   +4 more
core   +1 more source

Considerations for physicians using ketamine for sedation of children in emergency departments [PDF]

Clinical and Experimental Emergency Medicine, 2017
Objective Ketamine use in emergency departments (EDs) for procedural sedation and analgesia is becoming increasingly common. However, few studies have examined patient factors related to adverse events associated with ketamine.
Woo Sung Kim, Ji Yeon Ku, Hanbyul Choi, Hyo Jeong Choi, Ho Jung Kim, Bora Lee   +5 more
doaj   +1 more source

Efficacy of propofol versus ketamine in modified electroconvulsive therapy: A prospective randomized control trial

Journal of Acute Disease, 2022
Objective: To investigate the effects of propofol and ketamine on seizure duration, hemodynamics, and recovery of electroconvulsive therapy (ECT).
Debarshi Guha, Kiran Sheshadri, Shalendra Singh, Sonia Bhan   +3 more
doaj   +1 more source

Administration of Nebulized Ketamine for Managing Acute Pain in the Emergency Department: A Case Series [PDF]

, 2020
Ketamine administration in sub-dissociative doses in the emergency department (ED) results in effective pain relief in patients with acute traumatic and non-traumatic pain, chronic pain, and opioid-tolerant pain.
Butt, Mahlaqa, Drapkin, Jefferson, Hossain, Rukhsana, Likourezos, Antonios, Masoudi, Aidin, Motov, Sergey   +5 more
core  

Effects of an intravenous ketamine infusion on inflammatory cytokine levels in male and female Sprague–Dawley rats

Journal of Neuroinflammation, 2022
Background Ketamine, a multimodal dissociative anesthetic drug, is widely used as an analgesic following traumatic injury. Although ketamine may produce anti-inflammatory effects when administered after injury, the immunomodulatory properties of ...
Haley F. Spencer, Rina Y. Berman, Martin Boese, Michael Zhang, Sharon Y. Kim, Kennett D. Radford, Kwang H. Choi   +6 more
doaj   +1 more source

Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica) [PDF]

, 2018
The pig (Sus scrofa domestica) is an animal used as an experimental model in surgical procedures. This makes the use of anaesthesia necessary. The present study constitutes a comparison between two different ketamine/xylazine concentration protocols. One
Gargiulo, Pascual Angel, Giai, Marcos, Guevara, Manuel Alejandro, Lorenzo Aquaro, Sofía Ana   +3 more
core   +1 more source

Role of N-methyl-D-aspartate receptors in action-based predictive coding deficits in schizophrenia [PDF]

, 2017
Published in final edited form as:Biol Psychiatry. 2017 March 15; 81(6): 514–524. doi:10.1016/j.biopsych.2016.06.019.BACKGROUND: Recent theoretical models of schizophrenia posit that dysfunction of the neural mechanisms subserving predictive coding ...
Ford, Judith M., Gunduz-Bruce, Handan, Jaeger, Judith, Kort, Naomi S., Krystal, John H., Mathalon, Daniel H., Reinhart, Robert M.G., Roach, Brian J.   +7 more
core   +1 more source

Using transcranial direct-current stimulation (tDCS) to understand cognitive processing [PDF]

, 2016
Noninvasive brain stimulation methods are becoming increasingly common tools in the kit of the cognitive scientist. In particular, transcranial direct-current stimulation (tDCS) is showing great promise as a tool to causally manipulate the brain and ...
Cosman, Josh D., Fukuda, Keisuke, Reinhart, Robert M.G., Woodman, Geoffrey F.   +3 more
core   +1 more source