Results 31 to 40 of about 225,419 (363)
Ketamine infusion as a sedative-analgesic in severe ARDS (KISS)
Journal of Community Hospital Internal Medicine Perspectives, 2021 Rationale Ketamine has been used as a sedative analgesic in trauma setting, but data regarding its efficacy and safety is lacking in severe ARDS.
Ramakanth Pata +11 more
doaj +1 more source
The thermodynamic soliton theory of the nervous impulse and possible medical implications [PDF]
Progress in Biophysics and Molecular Biology 173 (2022) 24-35, 2022 The textbook picture of nerve activity is that of a propagating voltage pulse driven by electrical currents through ion channel proteins, which are gated by changes in voltage, temperature, pressure or by drugs. All function is directly attributed to single molecules. We show that this leaves out many important thermodynamic couplings between different
arxiv +1 more source
F1000Research, 2017 The efficacy of theN-methyl-D-aspartate receptor antagonist ketamine as an analgesic agent is still under debate, especially for indications such as chronic pain. To understand the efficacy of ketamine for relief of pain, we performed a literature search for relevant narrative and systematic reviews and meta-analyses.
Kelly Jonkman +5 more
openaire +3 more sources
Cortical Thickness Changes in Chronic Ketamine Users
Frontiers in Psychiatry, 2021 Background: Previous studies have examined the effects of long-term ketamine use on gray matter volume. But it is unclear whether chronic ketamine use alters cortical thickness and whether cortical thickness changes in chronic ketamine users are ...
Jun Zhong +7 more
doaj +1 more source
Frontiers in Neuroscience, 2021 Ketamine has been in use for over 50 years as a general anesthetic, acting primarily through blockade of N-methyl-D-aspartate receptors in the brain. Recent studies have demonstrated that ketamine also acts as a potent and rapid-acting antidepressant ...
Zachary Geiger +6 more
doaj +1 more source
Non-equilibrium brain dynamics as a signature of consciousness [PDF]
Phys. Rev. E 104, 014411 (2021), 2020 The cognitive functions of human and non-human primates rely on the dynamic interplay of distributed neural assemblies. As such, it seems unlikely that cognition can be supported by macroscopic brain dynamics at the proximity of thermodynamic equilibrium.
arxiv +1 more source
BJPsych Open, 2021 Background In the past two decades, subanaesthetic doses of ketamine have been demonstrated to have rapid and sustained antidepressant effects, and accumulating research has demonstrated ketamine's therapeutic effects for a range of psychiatric ...
Z. Walsh +7 more
semanticscholar +1 more source
Journal of Acute Disease, 2022 Objective: To investigate the effects of propofol and ketamine on seizure duration, hemodynamics, and recovery of electroconvulsive therapy (ECT).
Debarshi Guha +3 more
doaj +1 more source
BMC Anesthesiology, 2018 Background Ketamine and hyperoxia are widely used in obstetric and pediatric settings. Either ketamine or hyperoxia has been reported to cause neuroapoptosis in the developing brain, and ketamine-induced neuronal apoptosis may involve a compensatory ...
Changyi Wu +3 more
doaj +1 more source
Frontiers in Psychiatry, 2022 Ketamine has gained rapid popularity as a treatment option for treatment resistant depression (TRD). Though seen only in limited contexts, ketamine is a potential drug of abuse, addiction and diversion.
Brittany Chubbs +6 more
doaj +1 more source