Results 41 to 50 of about 235,967 (343)
Journal of Neuroinflammation, 2022 Background Ketamine, a multimodal dissociative anesthetic drug, is widely used as an analgesic following traumatic injury. Although ketamine may produce anti-inflammatory effects when administered after injury, the immunomodulatory properties of ...
Haley F. Spencer +6 more
doaj +1 more source
British Journal of Anaesthesia, 2018 The file associated with this record is under embargo until 12 months after publication, in accordance with the publisher's self-archiving policy. The full text may be available through the publisher links provided above. ; Since Domino and colleagues reported the first clinical use of ketamine more than half a century ago there have been many clinical
Hirota, K, Lambert, DG
openaire +4 more sources
ACS Chemical Neuroscience, 2020 Psilocybin shows efficacy to alleviate depression in human clinical trials for six or more months after only one or two treatments. Another hallucinogenic drug, esketamine, has recently been U.S.
M. Hibicke +4 more
semanticscholar +1 more source
Pharmacological Reports, 2021 Over the past 50 years, ketamine has solidified its position in both human and veterinary medicine as an important anesthetic with many uses. More recently, ketamine has been studied and used for several new indications, ranging from chronic pain to drug
S. Kohtala
semanticscholar +1 more source
Mis-anaesthetized society: expectancies and recreational use of ketamine in Taiwan
BMC Public Health, 2019 Background The popularity of ketamine for recreational use has been increasing in Asia, including Taiwan. Still, little known about the pattern of ketamine expectancies and whether such patterns are related to ketamine use.
Chao-Ming Chang +5 more
doaj +1 more source
International Journal of Neuropsychopharmacology, 2021 Background Ketamine has emerged as a fast-acting and powerful antidepressant, but no head to head trial has been performed, Here, ketamine is compared with electroconvulsive therapy (ECT), the most effective therapy for depression.
Joakim Ekstrand +9 more
semanticscholar +1 more source
(S)-(+)-Ketamine hydrochloride [PDF]
Acta Crystallographica Section E Structure Reports Online, 2008 The crystal structure of the title compound {systematic name: (S)-(+)-N-[1-(2-chloro-phen-yl)-2-oxocyclo-hexyl]meth-anam-in-ium chloride}, C(13)H(17)ClNO(+)·Cl(-), was determined at 90 (2) K. The (S)-(+)-ketamine hydro-chloride salt is a well known anesthetic compound and is dramatically more potent than its R isomer.
Jon Zubieta +3 more
openaire +4 more sources
Therapeutic Advances in Psychopharmacology, 2020 Ketamine, a drug introduced in the 1960s as an anesthetic agent and still used for that purpose, has garnered marked interest over the past two decades as an emerging treatment for major depressive disorder.
D. Matveychuk +6 more
semanticscholar +1 more source
Ketamine and the Future of Rapid-Acting Antidepressants.
Annual Review of Clinical Psychology, 2021 The therapeutic onset of traditional antidepressants is delayed by several weeks, and many depressed patients fail to respond to treatment altogether.
L. Riggs, T. Gould
semanticscholar +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source