Results 41 to 50 of about 174,609 (228)
Guidelines for ketamine use in clinical psychiatry practice
BJPsych OpenIn this editorial, we emphasise the efficacy and challenges of using ketamine in treatment-resistant depression. We highlight the need for comprehensive evidence-based guidelines to manage the use of both licensed and off-licence ketamine formulations ...
Luke A. Jelen +2 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu +10 more
wiley +1 more source
Effects of Perinatal Exposure to Ketamine on the Developing Brain
Frontiers in Neuroscience, 2019 Initially used as an analgesic and anesthetic, ketamine has unfortunately been abused as a popular recreational party drug due to its psychotropic effects. Over the last decade, ketamine has also emerged as an effective rapid-onset anti-depressant.
Hoi Man Cheung +3 more
doaj +1 more source
Translational Psychiatry, 2021 Intravenous (IV) subanesthetic doses of ketamine have been shown to reduce psychiatric distress in both major depressive (MDD) and posttraumatic stress disorder (PTSD).
Margaret T. Davis +4 more
doaj +1 more source
Clinical research progress on the antidepressant effects of ketamine
Sichuan jingshen weisheng, 2021 Ketamine has gained increasing attention as a novel antidepressant. This article reviews the clinical studies on the antidepressant and anti-suicidal properties of ketamine and its enantiomers （R-ketamine， S-ketamine）.
Fan Ni
doaj +1 more source
3D‐Printable, Honeycomb‐Inspired Tissue‐Like Bioelectrodes for Patient‐Specific Neural Interface
Advanced Materials, EarlyView.3D printed MRI‐compatible tissue‐like neural electrodes tailored to individual gyral patterns. This honeycomb‐inspired printable gel electrode (HiPGE) employs a bioinspired architecture with soft hydrogels, engineered to match the softness of brain tissue.
Marzia Momin +12 more
wiley +1 more source
IBRO Neuroscience Reports, 2021 Although ketamine, a multimodal dissociative anesthetic, is frequently used for analgesia and treatment-resistant major depression, molecular mechanisms of ketamine remain unclear.
Michael Zhang +4 more
doaj +1 more source
Study of a Novel Bi‐Layered Thermoplastic Polyurethane Patch for Congenital Diaphragmatic Hernia
Advanced Materials Interfaces, EarlyView.Large congenital diaphragmatic hernia remains a challenge due to the poor compatibility of current prostheses. To tackle this problem, a bilayer thermoplastic polyurethane patch with tunable mechanical properties is engineered, whose fibrous side supports rapid fibroblast and myoblast colonization, while the smooth film limits adhesions.
Guillaume Leks +14 more
wiley +1 more source
ContinenceKetamine induced uropathy has become a new bladder pain syndrome affecting the bladder, kidney, and quality of life in ketamine abusers. Ketamine-associated cystitis (KC) is an emerging public health concern, particularly among young adults who abuse ...
Hann-Chorng Kuo
doaj +1 more source
Ketamine Modulates Zic5 Expression via the Notch Signaling Pathway in Neural Crest Induction
Frontiers in Molecular Neuroscience, 2018 Ketamine is a potent dissociative anesthetic and the most commonly used illicit drug. Many addicts are women at childbearing age. Although ketamine has been extensively studied as a clinical anesthetic, its effects on embryonic development are poorly ...
Yu Shi +13 more
doaj +1 more source