A Comparison of xylazine/ketamine, diazepam/ketamine and acepromazine/ketamine anaesthesia in Rabbit [PDF]
The efficacy and safety of the recommended intramuscular (im) clinical doses of xylazine-ketamine (5mg-35mg/kg), diazepam-ketamine (5mg-60mg/kg) and acepromazine-ketamine (5mg-75mg/kg) post administration were obtained, evaluated and compared using the ...
Oguntoye, CO, Oke, BO
core +2 more sources
Ketamine Modulates Zic5 Expression via the Notch Signaling Pathway in Neural Crest Induction
Ketamine is a potent dissociative anesthetic and the most commonly used illicit drug. Many addicts are women at childbearing age. Although ketamine has been extensively studied as a clinical anesthetic, its effects on embryonic development are poorly ...
Yu Shi+13 more
doaj +1 more source
PurposeTo assess the effect of continuous ketamine administration in patients admitted to medical and cardiac intensive care units (ICUs) and received mechanical ventilation support.MethodsWe conducted a retrospective cohort study between March 2012 and ...
Hohyung Jung+6 more
doaj +1 more source
Thermodynamic properties and Hilbert space of the human brain [PDF]
Any macrosystem consists of many microparticles. According to statistical physics, the macroproperties of a system are realized as the statistical average of the corresponding microproperties. In our study, a model based on ensemble theory from statistical physics is proposed. Specifically, the functional connectivity (FC) patterns confirmed by Leading
arxiv
Abstract A lack of understanding of the mechanisms underlying osteoarthritis (OA) progression limits the development of effective long‐term treatments. Quantitatively tracking spatiotemporal patterns of cartilage and bone degeneration is critical for assessment of more appropriately targeted OA therapies.
Deva D. Chan+8 more
wiley +1 more source
Effects of Perinatal Exposure to Ketamine on the Developing Brain
Initially used as an analgesic and anesthetic, ketamine has unfortunately been abused as a popular recreational party drug due to its psychotropic effects. Over the last decade, ketamine has also emerged as an effective rapid-onset anti-depressant.
Hoi Man Cheung+3 more
doaj +1 more source
Ketamine-Medetomidine General Anesthesia Occurs With Alternation of Cortical Electrophysiological Activity Between High and Low Complex States [PDF]
Anesthetic agents are known to induce a range of alterations in cortical electrophysiological activity, such as the rise of signature patterns, changes in statistical properties, and altered dynamic behavior of neural records. Plenty of methods can be used to monitor these changes, among them complexity metrics demonstrated to have the power to ...
arxiv
Analysis and Model of Cortical Slow Waves Acquired with Optical Techniques [PDF]
Slow waves (SWs) are spatio-temporal patterns of cortical activity that occur both during natural sleep and anesthesia and are preserved across species. Even though electrophysiological recordings have been largely used to characterize brain states, they are limited in the spatial resolution and cannot target specific neuronal population.
arxiv +1 more source
Safety and efficacy of a propofol and ketamine based procedural sedation protocol in children with cerebral palsy undergoing botulinum toxin A injections. [PDF]
Background Pediatric patients with cerebral palsy (CP) often undergo intramuscular botulinum toxin (BoNT‐A) injections. These injections can be painful and may require procedural sedation.
Abu-Sultaneh, Samer+4 more
core +1 more source
Pharmacodynamic Interactions Between Ketamine and Psychiatric Medications Used in the Treatment of Depression:A Systematic Review [PDF]
Background The use of ketamine for depression has increased rapidly in the past decades. Ketamine is often prescribed as an add-on to other drugs used in psychiatric patients, but clear information on drug-drug interactions is lacking.
Bakker, Iris M+6 more
core +2 more sources