Results 81 to 90 of about 25,521 (211)

In vitro additive interaction between ketoconazole and antimony against intramacrophage Leishmania (Leishmania) amazonensis amastigotes.

open access: yesPLoS ONE, 2017
Leishmaniasis is a group of diseases caused by protozoa of Leishmania genus. The currently available treatments for this disease are expensive, present high toxicity and are associated to difficulties of healing and parasite resistance.
Débora Cristina de Oliveira Nunes   +7 more
doaj   +1 more source

Nanoemulsions for Skin Delivery of Essential Oils: A Systematic Review

open access: yesPhytotherapy Research, Volume 40, Issue 3, Page 847-872, March 2026.
ABSTRACT Essential oils (EOs) are recognized for their multiple health benefits. However, their high volatility, low stability, and limited water solubility limit their effective application. This systematic review aims to assess the use of nanoemulsions as delivery systems for the topical administration of EOs, highlighting their efficacy, safety, and
Thais Leticia Moreira da Silva   +3 more
wiley   +1 more source

Pharmacokinetics of Perampanel in Danish Paediatric Patients With Epilepsy Based on Therapeutic Drug Monitoring

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT We aimed to quantify inter‐ and intra‐patient variability in serum perampanel concentrations and assess whether concentrations predict efficacy or tolerability. We conducted a retrospective cohort study of 68 children and adolescents (< 18 years) treated at the Danish Epilepsy Centre (2017–2024), analysing 311 TDM samples.
Sara Angelucci   +5 more
wiley   +1 more source

Efficacy and Tolerability of Metyrapone in Mild Autonomous Cortisol Secretion: Real‐World Findings From Clinical Practice

open access: yesClinical Endocrinology, Volume 104, Issue 3, Page 215-221, March 2026.
ABSTRACT Objective Mild autonomous cortisol secretion (MACS) is associated with increased cardiometabolic risk factors including hypertension, type 2 diabetes and dyslipidaemia. By using evening doses of metyrapone, a short‐acting 11‐β hydroxylase inhibitor, it has been shown that it is possible to reset the abnormal circadian cortisol rhythm in MACS ...
Simon Berry   +3 more
wiley   +1 more source

Randomly Methylated β-Cyclodextrin Inclusion Complex with Ketoconazole: Preparation, Characterization, and Improvement of Pharmacological Profiles

open access: yesMolecules
As a powerful imidazole antifungal drug, ketoconazole’s low solubility (0.017 mg/mL), together with its odor and irritation, limited its clinical applications.
Yili Ding   +4 more
doaj   +1 more source

Supplementary Figure 2 from Sequential Use of the Androgen Synthesis Inhibitors Ketoconazole and Abiraterone Acetate in Castration-Resistant Prostate Cancer and the Predictive Value of Circulating Androgens

open access: gold, 2023
Won Bae Kim   +14 more
openalex   +1 more source

No Untoward Effect of Long‐Term Ketoconazole Administration on Electrocardiographic QT Interval in Patients with Cushing's Disease [PDF]

open access: hybrid, 2015
Martina De Martin   +6 more
openalex   +1 more source

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