Results 71 to 80 of about 41,377 (223)
Treatment of discospondylitis in dogs: A systematic review
Veterinary Record, EarlyView.Abstract Background Both medical and surgical techniques have been reported to manage canine discospondylitis, although data on clinical effectiveness and long‐term prognosis remain limited. Methods A systematic review of studies on treatment approaches, follow‐up data and investigation methods was conducted.
Vasileios Ioannis Vallios +4 more
wiley +1 more source
Pharmacokinetics of the cyclosporine-ketoconazole interaction in dogs [PDF]
, 1989 Numerous clinical reports have documented an increase in trough blood concentrations of cyclosporine in transplant recipients treated concomitantly with ketoconazole.
Burckart, GJ +7 more
core
Effect of ketoconazole-mediated CYP3A4 inhibition on clinical pharmacokinetics of panobinostat (LBH589), an orally active histone deacetylase inhibitor [PDF]
, 2011 Purpose: Panobinostat is partly metabolized by CYP3A4 in vitro. This study evaluated the effect of a potent CYP3A inhibitor, ketoconazole, on the pharmacokinetics and safety of panobinostat.
Paul Hamberg +10 more
core +2 more sources
The Journal of Dermatology, EarlyView.ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji +7 more
wiley +1 more source
Fungicidal activity plus reservoir effect allow short treatment courses with terbinafine in tinea pedis [PDF]
, 2008 Terbinafine, a synthetic allylamine, exerts fungicidal activity against dermatophytes, the causative pathogens of tinea pedis. As proven in numerous clinical trials, tinea pedis can be effectively and safely treated by topical terbinafine.
Korting, Hans Christian +2 more
core +1 more source
Allergy, EarlyView.ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier +221 more
wiley +1 more source
TREATMENT OF CUTANEOUS LEISHMANIASIS WITH KETOCONAZOLE CREAM
Journal of Research in Medical Sciences, 2001 n Iran. Many drugs have been suggested for treatment of CL but non of them proved to be effective. Recently ketoconazole has been used to treat CL patients and it has been reported that was effective.
A MOMENI, M AMINJAVAHERI, M.R OMIDGHAEMI
doaj
Comparison of three fluorescent CYP3A substrates in two vertebrate models: pig and Atlantic salmon
Animal, 2012 We investigated in vitro inhibitory effects of ketoconazole (KTZ) on cytochrome P450 activity in microsomes from pigs and Atlantic salmon. The following enzymatic reactions were studied: 7-benzyloxyresorufin and 7-ethoxyresorufin O-dealkylation (BROD and
V. Zlabek, G. Zamaratskaia
doaj +1 more source
The Diabetic Dog as a Translational Model for Human Islet Transplantation. [PDF]
, 2017 The dog model has served as the primary method for early development of many diabetes therapies, including pancreatic islet transplantation techniques and immunosuppressive protocols.
Adin, Christopher A, Gilor, Chen
core
Eletriptan in the management of acute migraine. An update on the evidence for efficacy, safety, and consistent response [PDF]
, 2016 Migraine is a multifactorial, neurological and disabling disorder, also characterized by several autonomic symptoms. Triptans, selective serotonin 5-HT1B/1D agonists, are the first-line treatment option for moderate-to-severe headache attacks.
Capi, Matilde +6 more
core +1 more source