Results 71 to 80 of about 26,568 (229)
Identification of Major Degradation products of Ketoconazole [PDF]
, 2011 Analytical methods were developed for the identification of major degradation products of Ketoconazole, an antifungal agent. The stressed degradation of Ketoconazole drug substance was performed under acid, base, thermal, photo and oxidative stress ...
Shirish SAHASRABUDHE, Rajendra A. Mhaske
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Smart Molecules, EarlyView.A series of novel pyrene‐linked heterocyclic pyrazoles were synthesized and structurally characterized. The compounds were evaluated for antimicrobial activity against selected bacterial and fungal strains, showing promising inhibitory effects. Molecular docking studies provided insights into binding interactions and structure–activity relationships ...
Dinkal V. Kasundra, Paresh N. Patel
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Mode of insertion of miconazole, ketoconazole and deacylated ketoconazole in lipid layers. A conformational analysis. [PDF]
, 1983 The conformation of three imidazole derivatives, miconazole, ketoconazole and deacylated ketoconazole (R 39 519) inserted in a lipid layer was calculated using a procedure of conformational analysis.
Van den Bossche, H. +5 more
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Treatment of discospondylitis in dogs: A systematic review
Veterinary Record, EarlyView.Abstract Background Both medical and surgical techniques have been reported to manage canine discospondylitis, although data on clinical effectiveness and long‐term prognosis remain limited. Methods A systematic review of studies on treatment approaches, follow‐up data and investigation methods was conducted.
Vasileios Ioannis Vallios +4 more
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Hepatic effects of ketoconazole in the male Swiss Webster mouse: temporal changes in drug metabolic parameters [PDF]
, 1990 There have been conflicting observations regarding the effects of ketoconazole on hepatic metabolism. The objectives of these studies were to determine whether ketoconazole was an enzyme inducer or inhibitor in the mouse and then to establish the time ...
C. J. Paul +4 more
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TREATMENT OF CUTANEOUS LEISHMANIASIS WITH KETOCONAZOLE CREAM
Journal of Research in Medical Sciences, 2001 n Iran. Many drugs have been suggested for treatment of CL but non of them proved to be effective. Recently ketoconazole has been used to treat CL patients and it has been reported that was effective.
A MOMENI, M AMINJAVAHERI, M.R OMIDGHAEMI
doaj
PLoS ONE, 2014 BackgroundThe antifungal compound ketoconazole has, in addition to its ability to interfere with fungal ergosterol synthesis, effects upon other enzymes including human CYP3A4, CYP17, lipoxygenase and thromboxane synthetase. In the present study, we have
Emmelie Björklund +3 more
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Addiction, EarlyView.Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson +13 more
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Comparision between therapeutic efficacy of terbinafine and ketoconazole in Tinea versicolor [PDF]
Background and Objective: Tinea versicolor is a common fungal infection of the skin caused by the dimorphic lipophilic yeast Pityrosporum orbicular (Malassezia furfur). Lesions begin as multiple small, circular macules of various colors.
نسیمی , مریم +2 more
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Ketoconazole induced torsades de pointes without concomitant use of QT interval-prolonging drug [PDF]
, 2005 Ketoconazole Induced Torsades de Pointes Ketoconazole is not known to be proarrhythmic without concomitant use of QT interval-prolonging drugs. We report a woman with coronary artery disease who developed a markedly prolonged QT interval and torsades de ...
Mok, NS, Lam, CW, Lo, YK, Tsui, PT
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