Results 81 to 90 of about 26,503 (228)

Hydrogel of Ketoconazole and PAMAM Dendrimers: Formulation and Antifungal Activity

open access: yesMolecules, 2012
Ketoconazole (KET), an imidazole derivative with well-known antifungal properties, is lipophilic and practically insoluble in water, therefore its clinical use has some practical disadvantages.
Elzbieta Tryniszewska   +4 more
doaj   +1 more source

Optimal model‐based design of experiments for parameter precision: Supercritical extraction case

open access: yesThe Canadian Journal of Chemical Engineering, Volume 104, Issue 7, Page 3775-3795, July 2026.
Abstract This study investigates the process of chamomile oil extraction from flowers. A parameter‐distributed model consisting of a set of partial differential equations is used to describe the governing mass transfer phenomena in a cylindrical packed bed with solid chamomile particles under supercritical conditions using carbon dioxide as a solvent ...
Oliwer Sliczniuk, Pekka Oinas
wiley   +1 more source

Topical delivery of acyclovir and ketoconazole

open access: yes, 2014
Context: Viral and fungal cutaneous manifestations are regularly encountered in immunocompromised HIV/AIDS individuals and can be treated by drugs such as acyclovir and ketoconazole, respectively. Objective: The aim of this study was to determine whether
Du Preez, Jan L.   +5 more
core   +1 more source

Effect of permeation enhancers on the penetration mechanism of transfersomal gel of ketoconazole

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2012
The aim of the present research work was to investigate the potential of transfersome formulations for transdermal delivery of Ketoconazole (KTZ). KTZ is a broad-spectrum antifungal agent that is active against a wide variety of fungi and yeasts.
Reshmy Rajan, Deepa T Vasudevan
doaj   +1 more source

Population Pharmacokinetics of Ticagrelor during Veno‐Arterial ECMO in Acute Coronary Syndrome: Model‐Informed Dosing Simulations

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 193-202, July 2026.
Although patients with acute coronary syndrome supported by veno‐arterial extracorporeal membrane oxygenation (VA‐ECMO) have a high risk of thrombosis and bleeding, antiplatelet pharmacology in this setting is not well defined. This prospective observational study investigated the population pharmacokinetics of ticagrelor and its active metabolite AR ...
Soyoung Kang   +9 more
wiley   +1 more source

Antioxidant and Cytotoxic Properties of Piper spp. Volatile Oils That Inhibit Pathogenic Microorganisms

open access: yesFlavour and Fragrance Journal, Volume 41, Issue 4, Page 935-942, July 2026.
The samples were fungicidal against Candida, with MICs ranging from 62.5 to 250 μg/mL, and fungistatic against Penicillium adametzii, Aspergillus flavus and A. niger, with MICs of 1000 μg/mL. The volatile oils of Piper aduncum and Piper marginatum reduced the viability of MDA‐MB231 cells.
Midiã R. Oliveira   +11 more
wiley   +1 more source

Pharmacokinetics of the cyclosporine-ketoconazole interaction in dogs [PDF]

open access: yes, 1989
Numerous clinical reports have documented an increase in trough blood concentrations of cyclosporine in transplant recipients treated concomitantly with ketoconazole.
Todo, S   +7 more
core  

Influence of food on the pharmacokinetics of ketoconazole

open access: yes, 1984
Eight healthy adults were given single oral doses of ketoconazole (200, 400, 600, and 800 mg) in the fasting state and with a standard breakfast at weekly intervals according to a balanced block design.
Ene, M. D.   +6 more
core   +2 more sources

Ketoconazole in the Prevention of Acute Respiratory Distress Syndrome

open access: yes, 1995
Objective:To describe the pharmacology of ketoconazole and examine the use of ketoconazole in critically ill surgical patients to prevent the development of acute respiratory distress syndrome (ARDS).Data Source:An English-language literature search from
Ivan L Maldonado   +2 more
core   +1 more source

Bilateral Ulcers in Protothecosis: A Diagnostic Challenge

open access: yes
International Journal of Dermatology, EarlyView.
Waratchaya Panjapakkul   +4 more
wiley   +1 more source

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