Results 101 to 110 of about 26,503 (228)
Nano Select, Volume 7, Issue 6, June 2026.The introduction covers the background and significance of conjunctivitis. It continues with a review of etiology, epidemiology, and clinical manifestations. Diagnostic methods are described, followed by discussions on pathophysiology and classification. Current treatment strategies, preventive measures, and therapeutic challenges are analyzed.
Xia Linkang +11 more
wiley +1 more source
Ketoconazole induced torsades de pointes without concomitant use of QT interval-prolonging drug
, 2005 Ketoconazole Induced Torsades de Pointes Ketoconazole is not known to be proarrhythmic without concomitant use of QT interval-prolonging drugs. We report a woman with coronary artery disease who developed a markedly prolonged QT interval and torsades de ...
Mok, NS, Lam, CW, Lo, YK, Tsui, PT
core +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.ABSTRACT The topoisomerase I inhibitor payload (DXd) released from the human epidermal growth factor receptor 2‐targeted antibody–drug conjugate (ADC) trastuzumab deruxtecan (T‐DXd) is eliminated by hepatic uptake via OATP1B1/3, metabolism by CYP3A, biliary excretion via P‐glycoprotein and breast cancer resistance protein, and urinary excretion.
Akiko Watanabe +6 more
wiley +1 more source
PLoS ONE, 2014 BackgroundThe antifungal compound ketoconazole has, in addition to its ability to interfere with fungal ergosterol synthesis, effects upon other enzymes including human CYP3A4, CYP17, lipoxygenase and thromboxane synthetase. In the present study, we have
Emmelie Björklund +3 more
doaj +1 more source
The Journal of Dermatology, Volume 53, Issue 6, Page 867-879, June 2026.ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji +7 more
wiley +1 more source
The interaction of miconazole and ketoconazole with lipids.
, 1982 Staphylococcus aureus can be protected by unsaturated unesterified fatty acids against the growth inhibitory effects of miconazole and ketoconazole observed at concentrations greater than 10(-6) M and greater than 10(-5) M, respectively.
Van den Bossche, H. +7 more
core +1 more source
Clinical and Translational Science, Volume 19, Issue 6, June 2026.ABSTRACT Quizartinib is an oral, potent, selective FMS‐like tyrosine kinase 3 (FLT3) inhibitor, approved for the treatment of FLT3‐internal tandem duplication (ITD)–positive acute myeloid leukemia (AML) and under investigation in patients with newly diagnosed FLT3‐ITD–negative AML.
YoungJun Yoo +8 more
wiley +1 more source
Ketoconazole pharmacokinetics during chronic dosing in adults with haematological malignancy
, 1986 Ketoconazole pharmacokinetics were determined in nine adults with haematological malignancy after one week on a 200 mg daily dose and later after one week on a 400 mg daily dose.
Daneshmend, T. K. +5 more
core +1 more source
Determination of Ketoconazole in Pharmaceutical Formulations
, 2014 Ketoconazole has been widely used as an antifungal drug that is formulated as tablets, cream and over-the-counter ketoconazole shampoo. The aim of this research was to study and to standardize an UV (ultraviolet spectrophotometric) method, potentiometry ...
Gjorgjeska, Biljana
core
Biochemical response to ketoconazole therapy in post-chemotherapy mCRPC patients.
, 2014 174 Background: Ketoconazole for the treatment of metastatic castration resistant prostate cancer (mCRPC) has never been investigated in randomized trials.
Camilla Nerstroem +6 more
core +1 more source