Results 121 to 130 of about 26,568 (229)
The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.Abstract Dihydroergotamine (DHE) prescribing information contains a boxed warning regarding the possibility of serious and/or life‐threatening peripheral ischemia with co‐administration of strong cytochrome P450 3A4 (CYP3A4) inhibitors. The effects of the strong CYP3A4 inhibitor itraconazole on the pharmacokinetics and safety of nasally administered ...
Detlef Albrecht +2 more
wiley +1 more source
From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression
MicrobiologyOpen, Volume 15, Issue 4, August 2026.Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez +3 more
wiley +1 more source
Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak +4 more
wiley +1 more source
Frontiers in MicrobiologyBackgroundThe emergence of tolerance to antifungal agents in Candida albicans complicates the treatment of fungal infections. Understanding the mechanisms underlying this tolerance is crucial for developing effective therapeutic strategies.ObjectiveThis ...
Lijun Zheng +3 more
doaj +1 more source
Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies
Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi +4 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 13, 14 July 2026.Chemical optimization of a novel pyridylpiperazine class yields two promising antimalarial candidates with an exceptional balance of metabolic stability and solubility. These optimized leads significantly protect mice from cerebral malaria, reducing parasitic load by up to 91.7%.
Douglas Davison da Silva Oliveira +8 more
wiley +1 more source
Fluconazole-resistant oral candidosis in a repeatedly treated female AIDS patient. [PDF]
, 1994 Bogner, Johannes R. +7 more
core +1 more source
Comparative study of oral and topical ketoconazole therapy in pityriasis versicolor [PDF]
, 2003 Introduction: Both topical and systemic ketoconazole are reported to be effective against pityriasis versicolor. Material and Methods: Forty patients suffering from pityriasis versicolor were treated either with oral ketoconazole 200 mg per day or 2 ...
V. K. Jain +2 more
core +2 more sources
Ketoconazole blocks adrenal steroidogenesis by inhibiting cytochrome P450-dependent enzymes [PDF]
, 1983 to interfere with steroidogenesis in patients and rat in vitro systems. In this study we attempted to elucidate the site of inhibition in the adrenal gland.
Robert A. Marcus +3 more
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