Results 211 to 220 of about 24,707 (302)

β‐Hydroxybutyrate Acts as an Exercise Mimetic to Protect the Aging Liver

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
β‐hydroxybutyrate (β‐HB) acts as an exercise mimetic to protect the aging liver. In aged models, exercise‐induced β‐HB delays liver aging by reversing macrophage senescence, blocking mtDNA/cGAS‐STING‐driven inflammation, and alleviating hepatocyte lipid deposition/PANoptosis.
Ke Li   +7 more
wiley   +1 more source

Ketogenesis is Dispensable for the Metabolic Adaptations to Caloric Restriction

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
In this study, we demonstrated that metabolic responses to a daily‐fed caloric restriction (CR) protocol remain robust in mice that cannot engage in canonical ketogenesis. This surprising finding is due to mice physiologically adapting to the daily bouts of fasting during CR by downregulating ketone production. ABSTRACT Caloric restriction (CR) extends
Chung‐Yang Yeh   +13 more
wiley   +1 more source

A mixed methods feasibility study of a ketogenic diet as treatment for Parkinson's disease. [PDF]

open access: yesFront Nutr
Worster K   +9 more
europepmc   +1 more source

Maternal Organ Growth: How the Adult Intestine Remodels During Pregnancy and Lactation

open access: yesDevelopment, Growth &Differentiation, Volume 68, Issue 1, January 2026.
ABSTRACT Adult organs exhibit remarkable plasticity, dynamically adjusting their size and function to meet physiological demands. The small‐intestinal epithelium, one of the most rapidly renewing tissues in mammals, undergoes extensive growth and remodeling in response to diet, injury, microbiota changes, and reproduction.
Tomotsune Ameku
wiley   +1 more source

Adipocyte-specific deletion of gp130 prevents ketogenic diet-induced hepatic steatosis. [PDF]

open access: yesHepatol Commun
Senkalfa B   +10 more
europepmc   +1 more source

A narrative review of meal management with the MiniMed™ 780G system: Evolution of dietary management in type 1 diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue S1, Page 61-68, January 2026.
Abstract Background Type 1 diabetes (T1D) meal management has long relied on structured carbohydrate counting and rigid bolus timing to achieve optimal glycaemic outcomes. However, these strategies impose a cognitive burden and are difficult to sustain in daily life. This narrative review evaluates how the MiniMed™ 780G Automated Insulin Delivery (AID)
Shannon Edd   +5 more
wiley   +1 more source

The Enteric Nervous System as a Mediator of Microbiota‐Gut‐Brain Interactions in Parkinson's Disease

open access: yesJournal of Neurochemistry, Volume 170, Issue 1, January 2026.
Parkinson's disease (PD) is a neurodegenerative disorder that is increasingly recognized as a gut‐brain disorder, involving gut dysfunction before the onset of motor symptoms. While many studies have focused on changes in gut microbiota, inconsistent results highlight the limitations of viewing PD through a microbiota‐only lens.
Luisa Valdetaro   +4 more
wiley   +1 more source

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