Results 231 to 240 of about 747,960 (296)

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 18, September 2026.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

High‐Protein Diet Ameliorates Cardiomyopathy in a Cardiac‐Specific AGL Knockout Mouse Model: Association With Upregulated Hepatic Gluconeogenesis

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACT Glycogen storage disease type IIIa (GSDIIIa) causes progressive cardiomyopathy, and current high‐fat dietary strategies lack consensus regarding long‐term cardiovascular safety. We evaluated the efficacy and safety of high‐protein versus high‐fat diets in a novel cardiac‐specific AGL knockout (CKO; AGLflox/flox/MHC‐Cre) mouse model to ...
Caiqi Du   +10 more
wiley   +1 more source

Ketogenic diet as a therapeutic strategy for neurodegenerative diseases: from mechanisms to translational challenges. [PDF]

open access: yesTransl Neurodegener
Salgueiro AM   +8 more
europepmc   +1 more source

From Common Pathway to Divergent Diseases: Metabolic Aspects of Inborn Errors of CoA Biosynthesis

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACT Coenzyme A (CoA) biosynthesis is a conserved, dynamically regulated pathway essential for mitochondrial energy production, fatty acid oxidation, lipid biosynthesis and protein acylation. Biallelic variants in PANK2, PPCS, PPCDC, and COASY cause rare inborn errors of CoA biosynthesis, associated with markedly different clinical phenotypes ...
Ivano Di Meo   +3 more
wiley   +1 more source

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