Results 221 to 230 of about 24,707 (302)

Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health

open access: yesJournal of Internal Medicine, Volume 299, Issue 1, Page 20-43, January 2026.
Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli   +12 more
wiley   +1 more source

Low-carbohydrate ketogenic diet in Mc Ardle's disease: a single-blinded randomized controlled trial. [PDF]

open access: yesJ Neurol
Martinuzzi A   +7 more
europepmc   +1 more source

The multifaceted roles of ketones in physiology

open access: yesExperimental Physiology, Volume 111, Issue 1, Page 1-13, 1 January 2026.
Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili   +3 more
wiley   +1 more source

Cardiovascular Dysfunction in Polycystic Ovary Syndrome: Mitochondrial and Inflammatory Mechanisms

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder that significantly increases cardiovascular disease (CVD) risk in women. While insulin resistance and dyslipidemia are established contributors, growing evidence highlights mitochondrial dysfunction and chronic low‐grade inflammation as central drivers of cardiovascular ...
Olabimpe Caroline Badejogbin   +8 more
wiley   +1 more source

Prurigo Pigmentosa Following Bariatric Surgery: A Comprehensive Clinicopathological Review

open access: yesDermatology Research and Practice, Volume 2026, Issue 1, 2026.
Prurigo pigmentosa (PP) is a rare inflammatory dermatosis first described in 1971 by Nagashima, classically predominantly affecting young women, particularly those of East Asian descent. Clinically, PP presents with pruritic, erythematous papules, which eventually form a reticulated pattern and resolve into post‐inflammatory hyperpigmentation.
Khalid Nabil Nagshabandi   +6 more
wiley   +1 more source

Pathophysiological Mechanisms and Nonpharmacological Interventions in Irritable Bowel Syndrome: Current Insights and Future Directions

open access: yesJournal of Nutrition and Metabolism, Volume 2026, Issue 1, 2026.
Irritable bowel syndrome, diagnosed using the ROME IV diagnostic criteria, is one of the most common dysfunctional disorders of the gastrointestinal system with a high global prevalence. Although symptom presentation is diverse, symptoms primarily manifest as abdominal pain, bloating, and alterations to bowel habits, negatively impacting quality of ...
Stefanie L. Y. Cheung   +2 more
wiley   +1 more source

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