Results 11 to 20 of about 9,766 (126)

Editorial: Ketogenic metabolic therapy as a treatment for mental health disorders. [PDF]

Front Nutr
Ede G, Zupec-Kania BA, Masino SA.
europepmc   +5 more sources

Successful application of dietary ketogenic metabolic therapy in patients with glioblastoma: a clinical study. [PDF]

Front Nutr
IntroductionGlioblastoma multiforme (GBM) ranks as one of the most aggressive primary malignant tumor affecting the brain. The persistent challenge of treatment failure and high relapse rates in GBM highlights the need for new treatment approaches. Recent research has pivoted toward exploring alternative therapeutic methods, such as the ketogenic diet,
Kiryttopoulos A, Evangeliou AE, Katsanika I, Boukovinas I, Foroglou N, Zountsas B, Cheva A, Nikolopoulos V, Zaramboukas T, Duraj T, Seyfried TN, Spilioti M.   +11 more
europepmc   +5 more sources

Ketogenic metabolic therapy in the remission of chronic major depressive disorder: a retrospective case study. [PDF]

Front Nutr
BackgroundThere is limited evidence describing the use of ketogenic metabolic therapy (KMT), also known as a ketogenic diet (KD), to achieve full remission of treatment-resistant major depressive disorder (MDD) in real-world clinical settings. This case study examines a 47-year-old woman with lifelong treatment-resistant MDD who achieved complete ...
Laurent N, Bellamy EL, Hristova D, Houston A.   +3 more
europepmc   +5 more sources

β-hydroxybutyrate recapitulates the beneficial effects of ketogenic metabolic therapy in polycystic kidney disease. [PDF]

iScience
Autosomal-dominant polycystic kidney disease (ADPKD) is a common monogenic disease characterized by the formation of fluid-filled renal cysts, loss of mitochondrial function, decreased fatty acid oxidation, increased glycolysis, and likely renal failure. We previously demonstrated that inducing a state of ketosis ameliorates or reverses PKD progression
Torres JA, Holznecht N, Asplund DA, Kroes BC, Amarlkhagva T, Haeffner MM, Sharpe EH, Koestner S, Strubl S, Schimmel MF, Kruger S, Agrawal S, Aceves BA, Thangaraju M, Weimbs T.   +14 more
europepmc   +7 more sources

The nervous system and metabolic dysregulation: emerging evidence converges on ketogenic diet therapy [PDF]

Frontiers in Neuroscience, 2012
A link between metabolism and brain function is clear. Since ancient times, epileptic seizures were noted as treatable with fasting, and historical observations of the therapeutic benefits of fasting on epilepsy were confirmed nearly 100 years ago ...
David N. Ruskin, Susan A Masino
doaj   +3 more sources

The effects of ketogenic metabolic therapy on mental health and metabolic outcomes in schizophrenia and bipolar disorder: a randomized controlled clinical trial protocol. [PDF]

Front Nutr
BackgroundSchizophrenia, schizoaffective disorder, and bipolar affective disorder are debilitating psychiatric conditions characterized by a chronic pattern of emotional, behavioral, and cognitive disturbances. Shared psychopathology includes the pre-eminence of altered affective states, disorders of thoughts, and behavioral control.
Longhitano C, Finlay S, Peachey I, Swift JL, Fayet-Moore F, Bartle T, Vos G, Rudd D, Shareef O, Gordon S, Azghadi MR, Campbell I, Sethi S, Palmer C, Sarnyai Z.   +14 more
europepmc   +7 more sources

Ketogenic Metabolic Therapy for Glioma. [PDF]

Cureus, 2022
This study describes a retrospective case series of patients with glioma who received ketogenic metabolic therapy through dietary adherence and intermittent fasting.A retrospective chart review of a single surgeon's clinic records was performed to identify patients who maintained nutritional ketosis for at least four months between January 2015 and ...
Smith KA, Hendricks BK, DiDomenico JD, Conway BN, Smith TL, Azadi A, Fonkem E.   +6 more
europepmc   +3 more sources

The Role of Ketogenic Metabolic Therapy on the Brain in Serious Mental Illness: A Review. [PDF]

J Psychiatr Brain Sci, 2022
In search of interventions targeting brain dysfunction and underlying cognitive impairment in schizophrenia, we look at the brain and beyond to the potential role of dysfunctional systemic metabolism on neural network instability and insulin resistance in serious mental illness.
Sethi S, Ford JM.
europepmc   +5 more sources

Consideration of Ketogenic Metabolic Therapy as a Complementary or Alternative Approach for Managing Breast Cancer. [PDF]

Front Nutr, 2020
Breast cancer remains as a significant cause of morbidity and mortality in women. Ultrastructural and biochemical evidence from breast biopsy tissue and cancer cells shows mitochondrial abnormalities that are incompatible with energy production through oxidative phosphorylation (OxPhos).
Seyfried TN, Mukherjee P, Iyikesici MS, Slocum A, Kalamian M, Spinosa JP, Chinopoulos C.   +6 more
europepmc   +8 more sources

A Review of Ketogenic Dietary Therapies for Epilepsy and Neurological Diseases: A Proposal to Implement an Adapted Model to Include Healthy Mediterranean Products

Foods, 2023
Based on the growing evidence of the therapeutic role of high-fat ketogenic dietary therapies (KDTs) for neurological diseases and on the protective effect of the Mediterranean diet (MD), it could be important to delineate a Mediterranean version of KDTs
Cinzia Ferraris, Monica Guglielmetti, Lenycia de Cassya Lopes Neri, Sabika Allehdan, Jamila Mohammed Mohsin Albasara, Hajar Hussain Fareed Alawadhi, Claudia Trentani, Simone Perna, Anna Tagliabue   +8 more
doaj   +1 more source