Ketogenic Diet in Cancer Prevention and Therapy: Molecular Targets and Therapeutic Opportunities
Current Issues in Molecular Biology, 2021 Although cancer is still one of the most significant global challenges facing public health, the world still lacks complementary approaches that would significantly enhance the efficacy of standard anticancer therapies.
Wamidh H. Talib +7 more
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Ketogenic metabolic therapy in conjunction with standard treatment for glioblastoma: A case report. [PDF]
Oncol LettGlioblastoma (GBM) is the most common primary malignant brain tumour in adults. The standard of care consists of surgical resection and concurrent chemoradiation, followed by adjuvant temozolomide chemotherapy. This protocol is associated with a median survival of 12-15 months, and 3 years.
Phillips MCL +4 more
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Understanding the experiences of ketogenic metabolic therapy for people living with varying levels of depressive symptoms: a thematic analysis [PDF]
Frontiers in NutritionJohn Turner, Bellamy Erin L
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Ketogenic diet in the treatment of cancer – Where do we stand?
Molecular Metabolism, 2020 Background: Cancer is one of the greatest public health challenges worldwide, and we still lack complementary approaches to significantly enhance the efficacy of standard anticancer therapies.
Daniela D. Weber +5 more
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Journal of Inherited Metabolic Disease, 2020 AbstractMetabolic epilepsies arise in the context of rare inborn errors of metabolism (IEM), notably glucose transporter type 1 deficiency syndrome, succinic semialdehyde dehydrogenase deficiency, pyruvate dehydrogenase complex deficiency, nonketotic hyperglycinemia, and mitochondrial cytopathies.
Gavrilovici, Cezar, Rho, Jong M
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Nutrition & Metabolism, 2021 Background The low carbohydrate, high fat ketogenic diet can be an effective anticonvulsant treatment in some pediatric patients with pharmacoresistant epilepsy. Its mechanism(s) of action, however, remain uncertain.
Susan A. Masino +4 more
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Corrigendum: Successful application of dietary ketogenic metabolic therapy in patients with glioblastoma: a clinical study. [PDF]
Front NutrKiryttopoulos A +11 more
europepmc +3 more sources
β-hydroxybutyrate recapitulates the beneficial effects of ketogenic metabolic therapy in polycystic kidney disease. [PDF]
iScienceAutosomal-dominant polycystic kidney disease (ADPKD) is a common monogenic disease characterized by the formation of fluid-filled renal cysts, loss of mitochondrial function, decreased fatty acid oxidation, increased glycolysis, and likely renal failure. We previously demonstrated that inducing a state of ketosis ameliorates or reverses PKD progression
Torres JA +14 more
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Hepatology, EarlyView., 2022 Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Animal-based ketogenic diet puts severe anorexia nervosa into multi-year remission: A case series
Journal of Metabolic Health, 2023 Background: Anorexia nervosa is a devastating condition that increases risk of death over five-fold and is associated with a high rate of relapse. Considering the growing field of metabolic psychiatry, anorexia can be framed as a ‘metabolic-psychiatric ...
Nicholas G. Norwitz +2 more
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