Results 51 to 60 of about 9,766 (126)

Electrical Control in Neurons by the Ketogenic Diet

open access: yesFrontiers in Cellular Neuroscience, 2018
The ketogenic diet is used as a diet treatment for drug-resistant epilepsy, but there are no antiepileptic drugs based on the ketogenic diet. The ketogenic diet changes energy metabolites (ketone bodies, glucose and lactate) in the brain, which ...
Nagisa Sada, Nagisa Sada, Tsuyoshi Inoue
doaj   +1 more source

Ketogenic therapy for schizophrenia: evidence, mechanisms, and clinical perspectives

open access: yesFrontiers in Pharmacology
IntroductionSchizophrenia is a chronic psychiatric disorder marked by significant cognitive and functional impairments. Current antipsychotic treatments offer limited benefit for negative symptoms and cognitive dysfunction while often exacerbating ...
Cristiano Chaves   +12 more
doaj   +1 more source

Practical guidelines for addressing common questions and misconceptions about the ketogenic diet

open access: yesJournal of Metabolic Health
Research publications on the ketogenic diet have experienced an exponential increase in recent years, driving clinical interest, which has expanded along with media interest.
Sarah M. Rice, Douglas B. Reynolds
doaj   +1 more source

Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy. [PDF]

open access: yesPLoS ONE, 2015
The Warburg effect and tumor hypoxia underlie a unique cancer metabolic phenotype characterized by glucose dependency and aerobic fermentation. We previously showed that two non-toxic metabolic therapies - the ketogenic diet with concurrent hyperbaric ...
A M Poff   +4 more
doaj   +1 more source

The Hypometabolic State of the Migraine Brain: Is a Ketogenic Diet the Answer?

open access: yesBrain and Behavior
Background Migraine pathophysiology involves a constellation of metabolic abnormalities. These interlinked contributory factors include mitochondrial dysfunction, an altered gut microbiome, neuroinflammation, oxidative stress, weight imbalance, and ...
Lakshini Gunasekera   +5 more
doaj   +1 more source

Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model.

open access: yesPLoS ONE, 2015
IntroductionNeuroblastoma is a malignant pediatric cancer derived from neural crest cells. It is characterized by a generalized reduction of mitochondrial oxidative phosphorylation.
Raphael Johannes Morscher   +7 more
doaj   +1 more source

Long-Term Ketogenic Diet Induces Metabolic Acidosis, Anemia, and Oxidative Stress in Healthy Wistar Rats

open access: yesJournal of Nutrition and Metabolism, 2020
Background. Ketogenic diet has been used as supportive therapy in a range of conditions including epilepsy, diabetes mellitus, and cancer. Objective.
Aryadi Arsyad   +9 more
doaj   +1 more source

Managing Metastatic Thymoma With Metabolic and Medical Therapy: A Case Report

open access: yesFrontiers in Oncology, 2020
Thymomas consist of neoplastic thymic cells intermixed with variable numbers of non-neoplastic lymphocytes. Metastatic thymomas are typically managed with non-curative chemotherapy to control tumor-related symptoms; no prolonged survival is expected ...
Matthew C. L. Phillips   +3 more
doaj   +1 more source

Ketogenic diet treatment in adults with glycogenosis type IIIa (Morbus Cori)

open access: yesClinical Nutrition Experimental, 2019
Summary: Background: Glycogen storage disease type IIIa (GSDIIIa) is a defect of the debranching enzyme (amylo-1,6-glucosidase) in glycogenolysis and has an effect on the muscles and the liver.
Tobias Fischer   +4 more
doaj   +1 more source

The Effect of a Ketogenic Diet on Cancer: Evidence From Systematic Reviews and Meta-Analyzes

open access: yesIntegrative Cancer Therapies
Background: Emerging evidence suggests that the ketogenic diet (KD) may support cancer treatment by improving metabolic parameters and reducing treatment-related side effects.
Majid Kamali Msc   +17 more
doaj   +1 more source

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