Results 41 to 50 of about 9,981 (208)

A Concise Review of Ketogenic Dietary Interventions in the Management of Rare Diseases

Journal of Nutrition and Metabolism, 2021
Dietary interventions are now being used as an adjunct therapy in the treatment of rare diseases. One such method is the high-fat, moderate-protein, and very low-carbohydrate diet which produces ketosis and therefore called the ketogenic diet.
D. Hettiarachchi, K. Lakmal, V. H. W. Dissanayake   +2 more
doaj   +1 more source

Can the ketogenic diet improve the hamstring muscle rupture? A narrative review [PDF]

Journal of Sports and Rehabilitation Sciences
The ketogenic diet has garnered significant attention for its potential benefits in various health areas, including weight loss, neurological conditions, and metabolic diseases.
Saeid Emamdoost
doaj   +1 more source

Metabolic therapy for temporal lobe epilepsy in a dish: investigating mechanisms of ketogenic diet using electrophysiological recordings in hippocampal slices

Frontiers in Molecular Neuroscience, 2016
The hippocampus is prone to epileptic seizures and is a key brain region and experimental platform for investigating mechanisms associated with the abnormal neuronal excitability that characterizes a seizure.
Masahito Kawamura, David Ruskin, Susan A Masino   +2 more
doaj   +1 more source

The role of β-hydroxybutyrate testing in ketogenic metabolic therapies

Frontiers in Nutrition
Accurate assessment of dietary adherence and metabolic outcomes remains a critical challenge in most nutrition studies. Ketogenic metabolic therapies (KMTs) provide a unique advantage by inducing nutritional ketosis and enabling the use of ketone bodies as biomarkers of metabolic state.
Fante, Cristina, Spritzler, Franziska, Calabrese, Lori, Laurent, Nicole, Roberts, Caroline, Deloudi, Sofia   +5 more
openaire   +2 more sources

Complete remission of depression and anxiety using a ketogenic diet: case series

Frontiers in Nutrition
BackgroundThere is little data that describe the use of ketogenic metabolic therapy to achieve full remission of major depression and generalized anxiety disorder in clinical practice.
Lori Calabrese, Rachel Frase, Mariam Ghaloo   +2 more
doaj   +1 more source

Reduced pain and inflammation in juvenile and adult rats fed a ketogenic diet. [PDF]

PLoS ONE, 2009
The ketogenic diet is a high-fat, low-carbohydrate regimen that forces ketone-based rather than glucose-based cellular metabolism. Clinically, maintenance on a ketogenic diet has been proven effective in treating pediatric epilepsy and type II diabetes ...
David N Ruskin, Masahito Kawamura, Susan A Masino   +2 more
doaj   +1 more source

Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy [PDF]

Frontiers in Molecular Neuroscience, 2016
Malignant brain tumors are devastating despite aggressive treatments such as surgical resection, chemotherapy and radiation therapy. The average life expectancy of patients with newly diagnosed glioblastoma is approximately ~18 months. It is clear that increased survival of brain tumor patients requires the design of new therapeutic modalities ...
Woolf, EC, Syed, N, Scheck, AC
openaire   +4 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Role of DNA Methylation and Adenosine in Ketogenic Diet for Pharmacoresistant Epilepsy: Focus on Epileptogenesis and Associated Comorbidities

Frontiers in Neurology, 2019
Epilepsy is a neurological disorder characterized by a long term propensity to produce unprovoked seizures and by the associated comorbidities including neurological, cognitive, psychiatric, and impairment the quality of life.
Fan Chen, Xinghui He, Guoming Luan, Tianfu Li   +3 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source