Results 61 to 70 of about 9,766 (126)

From glucose to histone modification: sex-specific metabolic responses to ketogenic therapy in VM/Dk mice

Frontiers in Nutrition
IntroductionThe assessment of sex-specific effects in pre-clinical models is critical for improving the translatability of findings to clinical applications.
Sara E. Moss, Angela M. Poff, Apryl Moss, Janine M. DeBlasi, Dominic P. D’Agostino   +4 more
doaj   +1 more source

Low-Carbohydrate (Ketogenic) Diet in Children with Obesity: Part 1—Diet Impact on Anthropometric Indicators and Indicators of Metabolic Syndrome and Insulin Resistance

Diseases
Background: The ketogenic diet has been successfully used in the last 100 years in the treatment of epilepsy and other neurological disorders. In recent decades, it gained wider application in the treatment of obesity, metabolic syndrome, and type 2 ...
Ivanka N. Paskaleva, Nartsis N. Kaleva, Teodora D. Dimcheva, Petya P. Markova, Ivan S. Ivanov   +4 more
doaj   +1 more source

Therapeutic potential of β-hydroxybutyrate in the management of pancreatic neoplasms: exploring novel diagnostic and treatment strategies

Lipids in Health and Disease
Pancreatic neoplasm, a highly aggressive and often fatal cancer, poses challenges due to late detection and nonspecific symptoms. Therefore, both early diagnosis and appropriate therapeutic approaches are necessary to augment the condition of these ...
Mohammad Amin Vaezi, Samira Nekoufar, Ali Karami Robati, Vahid Salimi, Masoumeh Tavakoli-Yaraki   +4 more
doaj   +1 more source

Craniotomy Complicated by Severe Metabolic Acidosis Requiring Massive Transfusion in an Infant on Ketogenic Diet Therapy for Intractable Epilepsy

International Medical Case Reports Journal, 2022
Seth B Hayes,1,2 Dolly M Munlemvo,1 Holly C Gillis,1,2 Joseph D Tobias1,2 1Department of Anesthesiology & Pain Medicine, Nationwide Children’s Hospital, Columbus, OH, USA; 2Department of Anesthesiology & Pain Medicine, The Ohio State University College ...
Hayes SB, Munlemvo DM, Gillis HC, Tobias JD   +3 more
doaj  

The Effect of a Ketogenic Diet on Human Health and Diseases: A Literature Review

Quality in Sport
Introduction and Aim. The ketogenic diet (KD), rich in fats and low in carbohydrates, induces a state of ketosis and metabolic changes. Used for over a century in epilepsy treatment, it is also gaining popularity in the therapy of other conditions ...
Kinga Bielas, Ewa Chodkowska , Kinga Dominiczak, Katarzyna Szafrańska, Aleksandra Mucha, Aleksander Szeps, Bartosz Zabrzeński, Jessika Schendzielorz   +7 more
doaj   +1 more source

The Impact of the Ketogenic Diet on the Metabolic Profile, Hormonal Balance and Fertility in Women with PCOS

Quality in Sport
Introduction: Polycystic ovary syndrome(PCOS) is the most common endocrine disorder among women of reproductive age. It is characterized by clinical symptom caused by high androgen level such as  acne, hirsutism and irregular menstrual cycles.
Mariola Turemka, Aneta Mandziuk, Aleksandra Cygnarowicz, Aneta Klaudia Wojtas, Krystyna Zabojska, Urszula Korotko, Kinga Witowska, Mikołaj Biskupski, Negar Hosseinnejad, karolina Sacher   +9 more
doaj   +1 more source

How effective is ketogenic diet in sleep disorders ?

European Psychiatry
Introduction Sleep disorders vary widely and its treatment are based on a combination of life style changes and pharmacological therapy adapted to the primer health issue.
N. Kouki
doaj   +3 more sources

Ketogenic diets in clinical psychology: examining the evidence and implications for practice

Frontiers in Psychology
IntroductionThe application of ketogenic dietary interventions to mental health treatments is increasingly acknowledged within medical and psychiatric fields, yet its exploration in clinical psychology remains limited.
Nicole Laurent, Erin L. Bellamy, Donika Hristova, Ally Houston   +3 more
doaj   +1 more source

From ketogenic metabolism to targeted therapeutics: current advances in β-hydroxybutyrylation

Frontiers in Immunology
β-Hydroxybutyrylation (Kbhb) is a novel posttranslational modification (PTM) mediated by β-hydroxybutyrate (BHB). BHB, the core product of ketogenic metabolism, serves as its direct precursor and substrate.
Fangshuai Hu, Fangshuai Hu, Changming Liang, Changming Liang, Xu Zhang, Xu Zhang, Lishuai Xu, Lishuai Xu, Chengwei Wu, Chengwei Wu, Senlin Wan, Senlin Wan, Jiawei Wang, Jiawei Wang, Mengyun Wang, Mengyun Wang, Dawei Zhang, Dawei Zhang, Yongchun Liu, Yongchun Liu, Zhenyuan Li, Zhenyuan Li, Xiaoming Wang, Xiaoming Wang, Xiaoxu Huang, Li Xu, Li Xu, Li Xu   +27 more
doaj   +1 more source

Metabolism of fatty acids and ketone bodies for glioblastoma growth: Implications for Ketogenic Diet Therapy

, 2019
ABSTRACT Glioblastoma (GBM) metabolism has traditionally been characterized by a dependence on aerobic glycolysis, prompting use of the ketogenic diet as a potential therapy. We observed growth-promoting effects on U87 GBM of both ketone body and fatty acid (FA) supplementation under physiological glucose conditions.
Sperry, Jantzen, Le Belle, Janel E., Condro, Michael C., Guo, Lea, Braas, Daniel, Vanderveer-Harris, Nathan, Kim, Kristen K.O., Pope, Whitney B., Divakaruni, Ajit S., Lai, Albert, Christofk, Heather, Kornblum, Harley I.   +11 more
openaire   +2 more sources