Results 21 to 30 of about 16,187 (190)

Ketogenic diet as a metabolic therapy for bipolar disorder: Clinical developments [PDF]

Journal of Affective Disorders Reports, 2021
Abstract Background: Bipolar disorder is a neurodevelopmental illness characterized by severe biphasic changes in mood, energy, or thought. Key underlying metabolic pathologies thought to play a role include dysfunction in energy metabolism.
Brenda J. Yu, Ruya S. Oz, Shebani Sethi
openaire   +2 more sources

Successful application of dietary ketogenic metabolic therapy in patients with glioblastoma: a clinical study. [PDF]

Front Nutr
IntroductionGlioblastoma multiforme (GBM) ranks as one of the most aggressive primary malignant tumor affecting the brain. The persistent challenge of treatment failure and high relapse rates in GBM highlights the need for new treatment approaches. Recent research has pivoted toward exploring alternative therapeutic methods, such as the ketogenic diet,
Kiryttopoulos A, Evangeliou AE, Katsanika I, Boukovinas I, Foroglou N, Zountsas B, Cheva A, Nikolopoulos V, Zaramboukas T, Duraj T, Seyfried TN, Spilioti M.   +11 more
europepmc   +4 more sources

Progress in the Application and Scheme of the Ketogenic Diet in the Treatment of Metabolic Diseases

Shipin gongye ke-ji, 2023
Ketogenic diets have been shown to play a role in some metabolic diseases and neurodegenerative diseases as a low-carbohydrate, high-fat diets supplemented with appropriate protein. Ketogenic diets have been proven effective, but the mechanisms of action
Yuqi LI, Yongbo ZHOU, Yongjun SHAN, Shiying HUANG, Lixin ZHOU, Jian LI   +5 more
doaj   +1 more source

Ketogenic diets [PDF]

Current Opinion in Neurology, 2012
Despite myriad anticonvulsants available and in various stages of development, there are thousands of children and adults with epilepsy worldwide still refractory to treatment and not candidates for epilepsy surgery. Many of these patients will now turn to dietary therapies such as the ketogenic diet, medium-chain triglyceride diet, modified Atkins ...
Eric H, Kossoff, Adam L, Hartman
openaire   +2 more sources

Research Progress of Ketogenic Diet (KD) in Clinical Nutritional Adjuvant Therapy

Shipin gongye ke-ji, 2022
With the development of society and the increasing incidence of many chronic metabolic diseases, ketogenic diet(KD) has been paid more and more attention as a potential, clinical and nutritional adjuvant therapy.
Chenlin PEI, Dingqiang LU, Guangchang PANG   +2 more
doaj   +1 more source

Consideration of Ketogenic Metabolic Therapy as a Complementary or Alternative Approach for Managing Breast Cancer. [PDF]

Front Nutr, 2020
Breast cancer remains as a significant cause of morbidity and mortality in women. Ultrastructural and biochemical evidence from breast biopsy tissue and cancer cells shows mitochondrial abnormalities that are incompatible with energy production through oxidative phosphorylation (OxPhos).
Seyfried TN, Mukherjee P, Iyikesici MS, Slocum A, Kalamian M, Spinosa JP, Chinopoulos C.   +6 more
europepmc   +6 more sources

Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity

Cancer & Metabolism, 2022
Background Growing evidence supports the use of low-carbohydrate/high-fat ketogenic diets as an adjunctive cancer therapy. However, it is unclear which genetic, metabolic, or immunological factors contribute to the beneficial effect of ketogenic diets ...
Daniela D. Weber, Sepideh Aminzadeh-Gohari, Maheshwor Thapa, Anna-Sophia Redtenbacher, Luca Catalano, Tânia Capelôa, Thibaut Vazeille, Michael Emberger, Thomas K. Felder, René G. Feichtinger, Peter Koelblinger, Guido Dallmann, Pierre Sonveaux, Roland Lang, Barbara Kofler   +14 more
doaj   +1 more source

Ketogenic metabolic therapy in conjunction with standard treatment for glioblastoma: A case report. [PDF]

Oncol Lett
Glioblastoma (GBM) is the most common primary malignant brain tumour in adults. The standard of care consists of surgical resection and concurrent chemoradiation, followed by adjuvant temozolomide chemotherapy. This protocol is associated with a median survival of 12-15 months, and 3 years.
Phillips MCL, Thotathil Z, Dass PH, Ziad F, Moon BG.   +4 more
europepmc   +3 more sources

Ketogenic Diet in Cancer Prevention and Therapy: Molecular Targets and Therapeutic Opportunities

Current Issues in Molecular Biology, 2021
Although cancer is still one of the most significant global challenges facing public health, the world still lacks complementary approaches that would significantly enhance the efficacy of standard anticancer therapies.
Wamidh H. Talib, Asma Ismail Mahmod, Ayah Kamal, Hasan M. Rashid, Aya M. D. Alashqar, Samar Khater, Duaa Jamal, Mostafa Waly   +7 more
doaj   +1 more source

β-hydroxybutyrate recapitulates the beneficial effects of ketogenic metabolic therapy in polycystic kidney disease. [PDF]

iScience
Autosomal-dominant polycystic kidney disease (ADPKD) is a common monogenic disease characterized by the formation of fluid-filled renal cysts, loss of mitochondrial function, decreased fatty acid oxidation, increased glycolysis, and likely renal failure. We previously demonstrated that inducing a state of ketosis ameliorates or reverses PKD progression
Torres JA, Holznecht N, Asplund DA, Kroes BC, Amarlkhagva T, Haeffner MM, Sharpe EH, Koestner S, Strubl S, Schimmel MF, Kruger S, Agrawal S, Aceves BA, Thangaraju M, Weimbs T.   +14 more
europepmc   +6 more sources