Results 81 to 90 of about 16,187 (190)

Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model.

PLoS ONE, 2015
IntroductionNeuroblastoma is a malignant pediatric cancer derived from neural crest cells. It is characterized by a generalized reduction of mitochondrial oxidative phosphorylation.
Raphael Johannes Morscher, Sepideh Aminzadeh-Gohari, René Gunther Feichtinger, Johannes Adalbert Mayr, Roland Lang, Daniel Neureiter, Wolfgang Sperl, Barbara Kofler   +7 more
doaj   +1 more source

Managing Metastatic Thymoma With Metabolic and Medical Therapy: A Case Report

Frontiers in Oncology, 2020
Thymomas consist of neoplastic thymic cells intermixed with variable numbers of non-neoplastic lymphocytes. Metastatic thymomas are typically managed with non-curative chemotherapy to control tumor-related symptoms; no prolonged survival is expected ...
Matthew C. L. Phillips, Deborah K. J. Murtagh, Sanjay K. Sinha, Ben G. Moon   +3 more
doaj   +1 more source

The Hypometabolic State of the Migraine Brain: Is a Ketogenic Diet the Answer?

Brain and Behavior
Background Migraine pathophysiology involves a constellation of metabolic abnormalities. These interlinked contributory factors include mitochondrial dysfunction, an altered gut microbiome, neuroinflammation, oxidative stress, weight imbalance, and ...
Lakshini Gunasekera, Jason C. Ray, Helmut Butzkueven, Terence J. O'Brien, Elspeth Hutton, Neha Kaul   +5 more
doaj   +1 more source

Long-Term Ketogenic Diet Induces Metabolic Acidosis, Anemia, and Oxidative Stress in Healthy Wistar Rats

Journal of Nutrition and Metabolism, 2020
Background. Ketogenic diet has been used as supportive therapy in a range of conditions including epilepsy, diabetes mellitus, and cancer. Objective.
Aryadi Arsyad, Irfan Idris, Andi A. Rasyid, Rezky A. Usman, Kiki R. Faradillah, Wa Ode U. Latif, Zidni I. Lubis, Aminuddin Aminuddin, Ika Yustisia, Yulia Y. Djabir   +9 more
doaj   +1 more source

Spanish Ketogenic Mediterranean diet: a healthy cardiovascular diet for weight loss [PDF]

, 2008
Background Ketogenic diets are an effective healthy way of losing weight since they promote a non-atherogenic lipid profile, lower blood pressure and decrease resistance to insulin with an improvement in blood levels of glucose and insulin.
Joaquín Pérez-Guisado, Andrés Muñoz-Serrano, Ángeles Alonso-Moraga, J Pérez-Guisado, S Liu, TL Halton, W Kopp, J Pérez-Guisado, A Trichopoulou, M Osler, WC Willett, DB Panagiotakos, LA Álvarez-Sala, O Moreiras-Varela, F Perez-Jimenez, JS Perona, JA Paniagua, SD Wollin, MA Carluccio, CM Papamichael, D Mozaffarian, PD Tsitouras, LS Piers, BA Cassady, HM Dashti, M Noakes, CM Young, FL Benoit, J Pérez-Guisado, M Noakes, JJ Li, JW Beulens, JV Nielsen, G Boden, H Gin, HM Dashti, HM Dashti, JA Paniagua, E Gimeno, E Waterman, MI Covas, HM Roche, J Hartweg, M Naissides, KR Sargrad, SA McNaughton   +45 more
core   +2 more sources

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders [PDF]

, 2018
High-fat, low-carbohydrate diets, known as ketogenic diets, have been used as a non-pharmacological treatment for refractory epilepsy. A key mechanism of this treatment is thought to be the generation of ketones, which provide brain cells (neurons and ...
Augustin, Katrin, Cross, Helen, Eaton, Simon, Heales, Simon, Khabbush, Aziza, Orford, Michael, Walker, Matthew, Williams, Robin, Williams, Sophie   +8 more
core   +2 more sources

Ketogenic diet treatment in adults with glycogenosis type IIIa (Morbus Cori)

Clinical Nutrition Experimental, 2019
Summary: Background: Glycogen storage disease type IIIa (GSDIIIa) is a defect of the debranching enzyme (amylo-1,6-glucosidase) in glycogenolysis and has an effect on the muscles and the liver.
Tobias Fischer, Helen Njoroge, Ulrike Och, Ira Klawon, Thorsten Marquardt   +4 more
doaj   +1 more source

"Electro-clinical Syndromes" with onset in Paediatric Age. the highlights of the clinical-EEG, genetic and therapeutic advances [PDF]

, 2011
The genetic causes underlying epilepsy remain largely unknown, and the impact of available genetic data on the nosology of epilepsy is still limited.
PARISI, Pasquale, Alberto Verrotti, PAOLINO, MARIA CHIARA, CASTALDO, Rosa, Filomena Ianniello, FERRETTI, ALESSANDRO, Francesco Chiarelli, VILLA, MARIA PIA   +7 more
core   +1 more source

Incidence and phenotypes of childhood-onset genetic epilepsies:a prospective population-based national cohort [PDF]

, 2019
Epilepsy is common in early childhood. In this age group it is associated with high rates of therapy-resistance, and with cognitive, motor, and behavioural comorbidity. A large number of genes, with wide ranging functions, are implicated in its aetiology,
Abdelnour, Ailsa McLellan, Alan Webb, Alice Jollands, Anagnostou, Anderson, Andreas Brunklaus, Angela Vincent, Appenzeller, Arsov, Barker, Baxter, Bayat, Bearden, Berg, Berg, Berg, Berkovic, Bethan Lang, Biervert, Boerma, Brunklaus, Brunklaus, Calum A Morrison, Capovilla, Caraballo, Ceulemans, Chiron, Christine Findlay, Coman, Coppola, Daniela T Pilz, de Lange, Devinsky, Devinsky, Devinsky, Devinsky, Di Giorgis, Ebrahimi-Fakhari, Elma Stephen, Eltze, Escayg, Fiest, French, Fukuoka, Gaily, Guerrini, Harkin, Hauser, Helbig, Heyne, Higurashi, Howell, Huang, Hully, Ishaq Abu-Arafeh, Jamie Andrew, Jamie Cruden, Jane MacDonnell, Jay Shetty, Jean McKnight, Johannesen, Joseph D Symonds, Kass, Kato, Kirsty Stewart, Krabbenborg, Kwan, Larsen, Lek, Lemke, Lesley Nairn, Liam Dorris, Lim, Lindy, Lotte, Louise A Diver, Margaret Wilson, Martin Kirkpatrick, Mary Callaghan, Mary O‘Regan, Meghan M Slean, Millichap, Milligan, Mullen, Mullen, Myers, Myers, Nellist, Ngugi, Olson, Palmer, Peng, Philip Brink, Pisano, Pong, Rosemary Grattan, Sameer M Zuberi, Sarah Gardiner, Sawyer, Scheffer, Shelagh Joss, Singh, Stewart MacLeod, Striano, Trump, Weckhuysen, Wilson, Wirrell, Wolff, Wu, Wynn, Zeng   +112 more
core   +4 more sources

From glucose to histone modification: sex-specific metabolic responses to ketogenic therapy in VM/Dk mice

Frontiers in Nutrition
IntroductionThe assessment of sex-specific effects in pre-clinical models is critical for improving the translatability of findings to clinical applications.
Sara E. Moss, Angela M. Poff, Apryl Moss, Janine M. DeBlasi, Dominic P. D’Agostino   +4 more
doaj   +1 more source