Results 171 to 180 of about 29,891 (282)

The proteomic effects of ketone bodies: implications for proteostasis and brain proteinopathies. [PDF]

Front Mol Neurosci, 2023
García-Velázquez L, Massieu L.
europepmc   +1 more source

Ketone Body Metabolism

Reactome - a curated knowledgebase of biological pathways, 2006
openaire   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Revisiting the thrifty substrate hypothesis: Ketone bodies as cardioprotective fuels in diabetes and SGLT2 inhibitor therapy. [PDF]

J Diabetes Investig
Suzuki Y, Amano T.
europepmc   +1 more source

Hemodynamic Effects of Ketone Bodies in Patients With Pulmonary Hypertension. [PDF]

J Am Heart Assoc, 2023
Nielsen R, Christensen KH, Gopalasingam N, Berg-Hansen K, Seefeldt J, Homilius C, Boedtkjer E, Andersen MJ, Wiggers H, Møller N, Bøtker HE, Mellemkjær S.   +11 more
europepmc   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Ketone Bodies Rescue Mitochondrial Dysfunction Via Epigenetic Remodeling. [PDF]

JACC Basic Transl Sci, 2023
Gambardella J, Jankauskas SS, Kansakar U, Varzideh F, Avvisato R, Prevete N, Sidoli S, Mone P, Wang X, Lombardi A, Santulli G.   +10 more
europepmc   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Therapeutic potential of ketone bodies on exercise intolerance in heart failure: looking beyond the heart. [PDF]

Cardiovasc Res
Soni S, Skow RJ, Foulkes S, Haykowsky MJ, Dyck JRB.   +4 more
europepmc   +1 more source

Effects of ketone bodies on energy expenditure, substrate utilization, and energy intake in humans. [PDF]

J Lipid Res, 2023
Fernández-Verdejo R, Mey JT, Ravussin E.   +2 more
europepmc   +1 more source