Results 181 to 190 of about 57,304 (300)

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song, HyunJi Lee, Youngshik Choe, Hyeyoung Lee   +3 more
wiley   +1 more source

Ketone bodies and cancer risk in the general population: The prevention of renal and vascular end-stage disease (PREVEND) study. [PDF]

Eur J Clin Invest
Luo L, Knol MGE, Kieneker LM, van der Vegt B, Bakker SJL, Gruppen EG, de Boer RA, Aboumsallem JP, Connelly MA, Dullaart RPF, Gansevoort RT.   +10 more
europepmc   +1 more source

Fasting Ketone Bodies and Incident Type 2 Diabetes in the General Population. [PDF]

Diabetes, 2023
Szili-Torok T, de Borst MH, Garcia E, Gansevoort RT, Dullaart RPF, Connelly MA, Bakker SJL, Tietge UJF.   +7 more
europepmc   +1 more source

Movement Disorders in Developmental and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Monogenic developmental and epileptic encephalopathies (DEE) frequently feature co‐occurring movement disorders. Gene discovery has expanded epilepsy‐dyskinesia syndromes (EDS) from classic associations such as stereotypies in Rett syndrome to PRRT2‐related infantile seizures with paroxysmal dyskinesia and crouched gait in SCN1A ...
Shekeeb Mohammad, Darius Ebrahimi‐Fakhari, Hugo Morales‐Briceno   +2 more
wiley   +1 more source

Ketone Bodies in the Regulation of Myocardial Perfusion in Cardiovascular Disease: Metabolic and Vasodilatory Effects. [PDF]

Int J Mol Sci
Aromiwura AA, Gouwens KR, Nguyen DC, Sztukowska M, Didelot L, Kalra DK.   +5 more
europepmc   +1 more source

Circulating ketone bodies and cardiovascular outcomes: the MESA study. [PDF]

Eur Heart J, 2023
Shemesh E, Chevli PA, Islam T, German CA, Otvos J, Yeboah J, Rodriguez F, deFilippi C, Lima JAC, Blaha M, Pandey A, Vaduganathan M, Shapiro MD.   +12 more
europepmc   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Endogenous Ketone Bodies Are Associated with Metabolic Vulnerability and Disability in Multiple Sclerosis. [PDF]

Nutrients
Wicks TR, Shalaurova I, Wolska A, Browne RW, Weinstock-Guttman B, Zivadinov R, Remaley AT, Otvos JD, Ramanathan M.   +8 more
europepmc   +1 more source

The proteomic effects of ketone bodies: implications for proteostasis and brain proteinopathies. [PDF]

Front Mol Neurosci, 2023
García-Velázquez L, Massieu L.
europepmc   +1 more source