Results 191 to 200 of about 57,304 (300)

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Circulating FGF21 and Ketone Bodies Modify the Risk of MASLD and Mortality: Insights from the PREVEND Cohort Study. [PDF]

Int J Mol Sci
Chvatal-Medina M, Li Y, Dam WA, Connelly MA, Moshage H, Bakker SJL, Dullaart RPF, Post A.   +7 more
europepmc   +1 more source

Hemodynamic Effects of Ketone Bodies in Patients With Pulmonary Hypertension. [PDF]

J Am Heart Assoc, 2023
Nielsen R, Christensen KH, Gopalasingam N, Berg-Hansen K, Seefeldt J, Homilius C, Boedtkjer E, Andersen MJ, Wiggers H, Møller N, Bøtker HE, Mellemkjær S.   +11 more
europepmc   +1 more source

Characteristics, properties and limitations of per‐ or polyfluoroalkyl substances (PFASs) and fluoropolymers

Polymer International, EarlyView.
An overview and categorization of man‐made per‐ or polyfluoroalkyl substances (PFASs) including low‐molar‐mass and high‐molar‐mass fluorochemicals, and their international regulations is presented. Though certain PFASs are toxic, bioaccumulative and cross the human cellular membranes, others, such as fluoropolymers, are safe, reliable and involved in ...
Bruno Améduri
wiley   +1 more source

Revisiting the thrifty substrate hypothesis: Ketone bodies as cardioprotective fuels in diabetes and SGLT2 inhibitor therapy. [PDF]

J Diabetes Investig
Suzuki Y, Amano T.
europepmc   +1 more source

Ketone Bodies Rescue Mitochondrial Dysfunction Via Epigenetic Remodeling. [PDF]

JACC Basic Transl Sci, 2023
Gambardella J, Jankauskas SS, Kansakar U, Varzideh F, Avvisato R, Prevete N, Sidoli S, Mone P, Wang X, Lombardi A, Santulli G.   +10 more
europepmc   +1 more source

Gene-environment interactions determine risk for dementia: the influence of lifestyle on genetic risk for dementia. [PDF]

, 2019
Lein, Pamela J, Patten, Kelley T
core  

Living Well With Type 1 Diabetes in Middle School: A Student‐Centered Perspective

Psychology in the Schools, EarlyView.
ABSTRACT Type 1 diabetes (T1D) is among the most common chronic illnesses affecting children and adolescents, meaning that all schools regularly include students with T1D. Supporting their well‐being requires understanding how they experience middle school to address their specific needs.
Isabelle Joing, Gaëlle Marais, Aurore Huchez, Elodie Lespagnol, Elsa Heyman   +4 more
wiley   +1 more source

Branched‐Chain Amino and Keto Acids Reduce Hepatocyte Lipid Droplet Size and Number via Distinct Proteomic Pathways

PROTEOMICS, EarlyView.
ABSTRACT Branched‐chain amino acids (BCAA) and their corresponding keto acids (BCKA) have been associated with changes in hepatic lipid metabolism and the resulting alterations in intracellular triglyceride concentrations. In this study, we utilized a previously established hepatocyte model to investigate the impact of BCAA and BCKA supplementation on ...
Jayasimha R. Daddam, Mounica Sura, Edward Kolodziej, Maria Gojcaj, Zheng Zhou   +4 more
wiley   +1 more source

Therapeutic potential of ketone bodies on exercise intolerance in heart failure: looking beyond the heart. [PDF]

Cardiovasc Res
Soni S, Skow RJ, Foulkes S, Haykowsky MJ, Dyck JRB.   +4 more
europepmc   +1 more source