Results 241 to 250 of about 4,666,601 (266)

Neuroprotective Properties of Ketone Bodies

2011
Ketosis, as with fasting or induced by ketogenic diet, continues to be explored as a strategy toward the treatment of neuropathologies and disease. Exogenous administration of anaplerotic compounds has shown promise as they rescue oxidatively stressed tissues and has shown to improve overall function in liver and heart, but little is known about their ...
Kui Xu, Joseph C. LaManna, Michelle Puchowicz   +2 more
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Effects of Ketone Bodies on Endurance Exercise

Current Sports Medicine Reports, 2018
Priorities for every athlete include improving endurance performance, optimizing training, nutrition, and recovery. Nutritional strategies are crucial to support athletes to perform at the highest level, and considering that muscular and hepatic glycogen stores are limited, alternative strategies to maximize fat metabolism have been suggested.
Sansone, Massimiliano, Sansone, Andrea, Borrione, Paolo, Romanelli, Francesco, Di Luigi, Luigi, Sgrò, Paolo   +5 more
openaire   +5 more sources

Cerebral ketone body metabolism

Journal of Inherited Metabolic Disease, 2004
SummaryKetone bodies (KBs) are an important source of energy for the brain. During the neonatal period, they are also precursors for the synthesis of lipids (especially cholesterol) and amino acids. The rate of cerebral KB metabolism depends primarily on the concentration in blood; high concentrations occur during fasting and on a high‐fat diet ...
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Increases in circulating levels of ketone bodies and cardiovascular protection with SGLT2 inhibitors: Is low‐grade inflammation the neglected component?

Diabetes, obesity and metabolism, 2018
Recent clinical trials have demonstrated a strong cardiovascular (CV) protective effect of sodium/glucose cotransporter (SGLT) 2 inhibitors, a recently introduced class of hypoglycaemic agents.
F. Prattichizzo, V. De Nigris, S. Micheloni, L. La Sala, A. Ceriello   +4 more
semanticscholar   +1 more source

Model of the kinetics of ketone bodies in humans

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1982
The kinetics of ketone bodies was studied in normal humans by giving a combined bolus intravenous injection of labeled acetoacetate ([14C]AcAc) and D(--)-beta-hydroxybutyrate (beta-[14C]-OHB) to seven subjects after an overnight fast, on two different occasions, and by collecting frequent blood samples for 100 min. Kinetic data were analyzed with both
COBELLI, CLAUDIO, Nosadini R, TOFFOLO, GIANNA MARIA, McCulloch A, AVOGARO, ANGELO, TIENGO, ANTONIO, Alberti KG   +6 more
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Ketone body metabolism and its defects

Journal of Inherited Metabolic Disease, 2014
AbstractAcetoacetate (AcAc) and 3‐hydroxybutyrate (3HB), the two main ketone bodies of humans, are important vectors of energy transport from the liver to extrahepatic tissues, especially during fasting, when glucose supply is low. Blood total ketone body (TKB) levels should be evaluated in the context of clinical history, such as fasting time and ...
Fukao, Toshiyuki, Mitchell, Grant, Sass, Jörn Oliver, Hori, Tomohiro, Orii, Kenji, Aoyama, Yuka   +5 more
openaire   +3 more sources

Effect of ketone bodies on cardiac metabolism

American Journal of Physiology-Legacy Content, 1965
The effect of acetoacetate infusion on myocardial metabolism was studied in 13 dogs at varying concentrations of acetoacetate. Acetoacetate was extracted by the myocardium at arterial levels of from 1 to 54 mg/100 ml. At arterial levels of above 60 mg/100 ml, extraction of acetoacetate by the heart was very small.
Sigmundur Gudbjarnason, E. Bassenge, P. Schollmeyer, Richard J. Bing, G. Blümchen, V. E. Wendt   +5 more
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Ketone bodies in cold-acclimated rats

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1983
Acclimation temperature (28 or 5 degrees C) modifies acetoacetate (AA) and beta-hydroxybutyrate (BOH) levels in blood and liver. In the fed state AA and BOH levels were increased in blood and liver of 5 degrees C adapted rats. In the fasting state (24 or 48 hr) an antiketotic action of cold acclimation was observed.
Monique Cadot, Marc Goubern
openaire   +3 more sources

The alanine-ketone body cycle hypothesis

Metabolism, 1982
SCOPUS: ar.j ; info:eu-repo/semantics ...
Fery, Françoise, Balasse, Edmond
openaire   +3 more sources

KETONE BODY METABOLISM IN NUTRITIONAL MYOPATHY

Canadian Journal of Biochemistry, 1964
A study was conducted on the metabolism of ketone bodies in tissue preparations from normal and dystrophic chicks. The data indicated that the production of ketone bodies in liver homogenates, as a result of fatty acid oxidation, was not markedly altered by development of the dystrophic condition.
openaire   +3 more sources