Ketoprofen as an emerging contaminant: occurrence, ecotoxicity and (bio)removal [PDF]
Frontiers in Microbiology, 2023 Ketoprofen, a bicyclic non-steroidal anti-inflammatory drug commonly used in human and veterinary medicine, has recently been cited as an environmental contaminant that raises concerns for ecological well-being.
Elena Tyumina +9 more
doaj +2 more sources
Formulation and In Vitro Evaluation of Matrix Tablets Containing Ketoprofen–Beta Cyclodextrin Complex for Enhanced Rheumatoid Arthritis Therapy: Experimental and Computational Insights [PDF]
PharmaceuticsBackground: Rheumatoid arthritis is a chronic autoimmune disease that leads to severe disability and requires improved therapeutic strategies to optimize anti-inflammatory treatment.
Monica Stamate Cretan +8 more
doaj +2 more sources
Selective Mapping of Brain COX-1 with [11C]PS13: Pharmacokinetic Evidence from human PET Imaging [PDF]
IBRO Neuroscience ReportsBackground and aim: Arachidonic acid is converted by cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) to prostaglandin H2, which has proinflammatory properties.
Kiana Orangi +13 more
doaj +2 more sources
Physical stability and dissolution of ketoprofen nanosuspension formulation: Polyvinylpyrrolidone and Tween 80 as stabilizers [PDF]
Pharmacia, 2023 This study was conducted to improve the dissolution of ketoprofen in nanosuspensions. Ketoprofen nanosuspensions were prepared by a solvent evaporation method using polyvinylpyrrolidone (PVP) and Tween 80 as stabilizers at varied ratios with ketoprofen ...
Tengku Ismanelly Hanum +3 more
doaj +3 more sources
Administration of ketoprofen in postpartum sows to control the incidence of post-parturient disorders and improve piglet survival rate [PDF]
Animal Bioscience, 2023 Objective Inflammation and pain management in postpartum hyperprolific sows is currently an important animal welfare issue in the swine industry. The present study investigates effects of ketoprofen treatment on the incidence of post-parturient disorders,
Suwicha Jeeraphokhakul +7 more
doaj +1 more source
Macedonian Veterinary Review, 2023 The objective of this study was to examine the effect of ketoprofen with or without combination with xylazine on the level of cyclooxygenase-2 in mice. The intraperitoneal (i.p.) dose of ketoprofen and xylazine that caused an analgesic response in half ...
Khalil Abdullah Khalil +2 more
doaj +1 more source
Materials Proceedings, 2023 The aim of this paper was to exactly quantify the amount of pure ketoprofen within a pharmaceutical by a newly developed ultraviolet (UV) spectrophotometric method.
Cristian-Catalin Gavat
doaj +1 more source
Symmetric dimethyl arginine and N-acetyl-β-D-glucosaminidase lysozimuria of proximal renal tubules as a target for nephrotoxicity in patients with rheumatoid arthritis treated with disease modifying antirheumatic drugs [PDF]
Journal of Nephropathology, 2013 Background: The aim of this study was to determine the effect of initial therapy with some disease modifying antirheumatic drugs (DMARDs) (Methotrexate and Ketoprofen) on glomerular and tubular integrity in patients with Rheumatoid arthritis (RA ...
Dejan Spasovski +13 more
doaj +1 more source
Crystals, 2022 This study aims to improve the dissolution rate of ketoprofen by preparing multicomponent crystals with tromethamine. The multicomponent crystals (equimolar ratio) of ketoprofen and tromethamine were prepared by the solvent co-evaporation method.
Lili Fitriani +7 more
doaj +1 more source