Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) [PDF]
The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ...
Adamek +196 more
core +1 more source
Use of gastroprotective agents in recommended doses in hospitalized patients receiving NSAIDs: a drug utilization study [PDF]
OBJECTIVE: In recent years, studies investigated to what extend recommendations for co-prescribing gastroprotective agents in prevention of NSAID-induced gastrointestinal complications are followed in clinical practice.
Bilušić, Marinko +6 more
core +1 more source
Objective: The study aims to evaluate the analgesic effect of oral ketoprofen prior to copper intrauterine device (IUD) insertion on pain perception during the insertion procedure.Study design: A randomized double-blind controlled trial (Clinical Trials.
Ahmed M. Abbas +3 more
doaj +1 more source
In vitro kinetic release study of ketoprofen enantiomers from alginate metal complexes
Background To explore the release behavior of ketoprofen enantiomers from alginate-metal-complexes. Five mathematical models of drug release kinetics were investigated.
Ghaidaa Alkhayer +2 more
doaj +1 more source
Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
The effect of alcohol on the performance of lipase-immobilized enzymatic membrane reactor for esterification of (R,S)-ketoprofen [PDF]
The effect of alcohols on the performance of lipase-immobilized enzymatic membrane reactor (EMR) for enantioselective esterification of (R,S)-ketoprofen has been studied. In this work, mixed solvent medium was used and the (R)-ketoprofen was reacted with
Bhatia, Subhash +3 more
core
We report a general strategy for meta‐selective C–H arylation using aryl iodides and a Pd(II)/Pd(IV) catalytic system guided by a removable directing group. DFT and experimental studies reveal that counter anion tuning (acetate to trifluoroacetate) significantly enhances selectivity.
Jagrit Grover +6 more
wiley +1 more source
IN VITRO IRREVERSIBLE BINDING AND DEGRADATION OF (R)- AND (S)-KETOPROFEN GLUCURONIDES TO PLASMA PROTEINS [PDF]
This study describes the in vitro degradation studies of the diastereomeric ketoprofen glucuronides, under physiological conditions (pH 7.4, 37°C, (R)-ketoprofen glucuronide t½ = 30 min, (S)-ketoprofen glucuronide t½ = 70 min) and the irreversible ...
PETER J. HAYBALL, KELLIE L. TUCK
doaj
Phase Diagram and Thermodynamic Properties of Ketoprofen-Succinic Acid Binary Mixtures
The equilibrium phase diagram and thermodynamic properties of a mixture of drugs and additives are information related to various possible interaction processes between components.
Yudi Wicaksono +2 more
doaj +1 more source
Non-steroidal anti-inflammatory drugs (NSAIDs) (aspirin, ibuprofen, naproxen, ketoprofen, and diclofenac) were determined in three selected wastewater treatment plants (WWTPs) in southwestern India and the Gurupura River. The concentrations of the NSAIDs
Yerabham Praveenkumarreddy +10 more
doaj +1 more source

