Perioperative ketorolac use and postoperative acute kidney injury in elderly patients undergoing noncardiac surgery: a retrospective cohort study [PDF]
The use of nonsteroidal anti-inflammatory drugs, particularly ketorolac, in elderly patients is not recommended due to concerns about acute kidney injury (AKI).
Ah Ran Oh, Ji Won Lee, Chisong Chung
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The Effectiveness of Ketorolac in Relieving Pain Associated With Root Canal Therapy: A Systematic Review and Meta‐Analysis [PDF]
Objectives Effective management of post‐endodontic pain is crucial for patient comfort. Although ketorolac is used for this purpose, its efficacy relative to other analgesics remains uncertain.
Ruijing Ping +4 more
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Management of Post-Operative Inflammation After Cataract Surgery with Intracanalicular Dexamethasone Implant and Topical Ketorolac [PDF]
Kartik Gannamaneni,1 Jeremy N Shapiro,2 Harry Levine,3 Karthik Reddy,3,4 Stephen T Armenti,5 Shahzad I Mian3 1Indiana University School of Medicine, Indianapolis, IN, USA; 2Department of Ophthalmology, Johns Hopkins University, Baltimore, MD, USA ...
Gannamaneni K +5 more
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Postoperative Ketorolac Use and the Odds of a Nonunion in Operatively Treated Scaphoid Fractures [PDF]
Purpose: Ketorolac is a potent nonsteroidal anti-inflammatory drug that is beneficial in the ambulatory hand surgery setting. Reluctance exists in the use of nonsteroidal anti-inflammatory drugs, such as ketorolac, after operative treatment of fractures ...
Alexander D. Jeffs, MD +8 more
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Rocuronium-induced withdrawal movement: influence of ketorolac or a combination of lidocaine and ketorolac pretreatment [PDF]
BackgroundPain on injection of rocuronium is a common clinical problem. We compared the efficacy of lidocaine, ketorolac, and the 2 in combination as pretreatment for the prevention of rocuronium-induced withdrawal movement.MethodsFor this prospective ...
Younghoon Jeon +5 more
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Background and Aims: Many drugs have been tried as adjuvant to local anesthetic in different nerve blocks. Ketorolac is one of them, but it has never been used in pectoral nerve block.
Shimaa A Al-Touny +3 more
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Ketogal Safety Profile in Human Primary Colonic Epithelial Cells and in Mice
In our previous studies, a ketorolac–galactose conjugate (ketogal) showed prolonged anti-inflammatory and analgesic activity, causing less gastric ulcerogenic effect and renal toxicity than its parent drug ketorolac.
Federica Sodano +13 more
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Pharmacokinetics of Ketorolac Pentyl Ester, a Novel Ester Derivative of Ketorolac, in Rabbits
Ketorolac is a potent nonsteroidal anti-inflammatory drug. Recently, a novel ester of ketorolac, ketorolac pentyl ester, was synthesized. When prepared in injectable oil, the new agent demonstrated a long duration of action.
Jann-Inn Tzeng +4 more
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The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo
Background Rho-family GTPases, including Ras-related C3 botulinum toxin substrate 1 (Rac1) and cell division control protein 42 (Cdc42), are important modulators of cancer-relevant cell functions and are viewed as promising therapeutic targets.
Martha M. Grimes +6 more
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Analgesic, antipyretic and anti-inflammatory efficacy of ketorolac in the chicks
Now-a-days, there is a need for newly, non-addicted and effective analgesics with less side effects. Therefore, the present study evaluated the analgesic, antipyretic and anti-inflammatory efficacy of ketorolac in 7–21 days old broiler chicks and its ...
Y J MOUSA
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