Results 1 to 10 of about 11,650 (156)

Perioperative ketorolac use and postoperative acute kidney injury in elderly patients undergoing noncardiac surgery: a retrospective cohort study [PDF]

open access: yesScientific Reports
The use of nonsteroidal anti-inflammatory drugs, particularly ketorolac, in elderly patients is not recommended due to concerns about acute kidney injury (AKI).
Ah Ran Oh, Ji Won Lee, Chisong Chung
doaj   +2 more sources

The Effectiveness of Ketorolac in Relieving Pain Associated With Root Canal Therapy: A Systematic Review and Meta‐Analysis [PDF]

open access: yesClinical and Experimental Dental Research
Objectives Effective management of post‐endodontic pain is crucial for patient comfort. Although ketorolac is used for this purpose, its efficacy relative to other analgesics remains uncertain.
Ruijing Ping   +4 more
doaj   +2 more sources

Management of Post-Operative Inflammation After Cataract Surgery with Intracanalicular Dexamethasone Implant and Topical Ketorolac [PDF]

open access: yesClinical Ophthalmology
Kartik Gannamaneni,1 Jeremy N Shapiro,2 Harry Levine,3 Karthik Reddy,3,4 Stephen T Armenti,5 Shahzad I Mian3 1Indiana University School of Medicine, Indianapolis, IN, USA; 2Department of Ophthalmology, Johns Hopkins University, Baltimore, MD, USA ...
Gannamaneni K   +5 more
doaj   +2 more sources

Postoperative Ketorolac Use and the Odds of a Nonunion in Operatively Treated Scaphoid Fractures [PDF]

open access: yesJournal of Hand Surgery Global Online
Purpose: Ketorolac is a potent nonsteroidal anti-inflammatory drug that is beneficial in the ambulatory hand surgery setting. Reluctance exists in the use of nonsteroidal anti-inflammatory drugs, such as ketorolac, after operative treatment of fractures ...
Alexander D. Jeffs, MD   +8 more
doaj   +2 more sources

Rocuronium-induced withdrawal movement: influence of ketorolac or a combination of lidocaine and ketorolac pretreatment [PDF]

open access: yesKorean Journal of Anesthesiology, 2013
BackgroundPain on injection of rocuronium is a common clinical problem. We compared the efficacy of lidocaine, ketorolac, and the 2 in combination as pretreatment for the prevention of rocuronium-induced withdrawal movement.MethodsFor this prospective ...
Younghoon Jeon   +5 more
doaj   +1 more source

Analgesic effect of ketorolac as an adjuvant to bupivacaine in ultrasound-guided pectoral nerve block (I + II) for patients undergoing modified radical mastectomy: A randomized controlled clinical trial

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2023
Background and Aims: Many drugs have been tried as adjuvant to local anesthetic in different nerve blocks. Ketorolac is one of them, but it has never been used in pectoral nerve block.
Shimaa A Al-Touny   +3 more
doaj   +1 more source

Ketogal Safety Profile in Human Primary Colonic Epithelial Cells and in Mice

open access: yesPharmaceuticals, 2021
In our previous studies, a ketorolac–galactose conjugate (ketogal) showed prolonged anti-inflammatory and analgesic activity, causing less gastric ulcerogenic effect and renal toxicity than its parent drug ketorolac.
Federica Sodano   +13 more
doaj   +1 more source

Pharmacokinetics of Ketorolac Pentyl Ester, a Novel Ester Derivative of Ketorolac, in Rabbits

open access: yesKaohsiung Journal of Medical Sciences, 2005
Ketorolac is a potent nonsteroidal anti-inflammatory drug. Recently, a novel ester of ketorolac, ketorolac pentyl ester, was synthesized. When prepared in injectable oil, the new agent demonstrated a long duration of action.
Jann-Inn Tzeng   +4 more
doaj   +1 more source

The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo

open access: yesBMC Cancer, 2021
Background Rho-family GTPases, including Ras-related C3 botulinum toxin substrate 1 (Rac1) and cell division control protein 42 (Cdc42), are important modulators of cancer-relevant cell functions and are viewed as promising therapeutic targets.
Martha M. Grimes   +6 more
doaj   +1 more source

Analgesic, antipyretic and anti-inflammatory efficacy of ketorolac in the chicks

open access: yesIndian Journal of Animal Sciences, 2019
Now-a-days, there is a need for newly, non-addicted and effective analgesics with less side effects. Therefore, the present study evaluated the analgesic, antipyretic and anti-inflammatory efficacy of ketorolac in 7–21 days old broiler chicks and its ...
Y J MOUSA
doaj   +1 more source

Home - About - Disclaimer - Privacy