Results 21 to 30 of about 11,650 (156)

Anaphylaxis as a Rare Side Effect of Ketorolac; a Case Report

Archives of Academic Emergency Medicine, 2020
Non-steroidal anti-inflammatory drugs (NSAIDs) constitute a broad spectrum of cyclooxygenase (COX) inhibitors suppressing prostaglandin synthesis. NSAIDs are used for treating various conditions such as pain, rheumatoid arthritis, osteoarthritis, and ...
Hesam Yousefi, Ali Sahebi, Mahtab Farahani, Mohamad Golitaleb   +3 more
doaj   +1 more source

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

ELECTROPHORESIS, EarlyView.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

The Influence of a Single Preoperative Ketorolac Dose on Postoperative Opiate Consumption for Ambulatory Knee Arthroscopy: A Double Blinded Placebo Controlled Study

Orthopaedic Journal of Sports Medicine, 2017
Objectives: Ketorolac is a non-steroidal anti-inflammatory known to decrease postoperative opiate requirements. While many studies have examined serial ketorolac doses over 48 hours, the optimal ketorolac dose for analgesia following ambulatory surgery ...
Harris Slone MD, Thomas Epperson MD, Cory Furse MD, Bethany Wolf PhD, Sylvia Wilson MD   +4 more
doaj   +1 more source

The Nonsteroidal Anti-Inflammatory Drug Ketorolac Alters the Small Intestinal Microbiota and Bile Acids Without Inducing Intestinal Damage or Delaying Peristalsis in the Rat

Frontiers in Pharmacology, 2021
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) induce significant damage to the small intestine, which is accompanied by changes in intestinal bacteria (dysbiosis) and bile acids.
Barbara Hutka, Bernadette Lázár, András S. Tóth, Bence Ágg, Bence Ágg, Szilvia B. László, Nóra Makra, Balázs Ligeti, Bálint Scheich, Kornél Király, Mahmoud Al-Khrasani, Dóra Szabó, Péter Ferdinandy, Péter Ferdinandy, Klára Gyires, Zoltán S. Zádori   +15 more
doaj   +1 more source

Network meta‐analysis of tocolytics in preterm labor: Establishing an evidence‐based treatment hierarchy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The choice of tocolytic drugs is one of the most debated aspects of preterm birth management. Objective This network meta‐analysis aimed to establish an evidence‐based hierarchy for tocolytics used in preterm labor by evaluating their efficacy in delaying delivery, safety, and neonatal outcomes.
Barbara Gardella, Chiara Cassani, Vittoria Morteo, Alessandra Marmiroli, Mattia Dominoni, Arsenio Spinillo   +5 more
wiley   +1 more source

Perspectives in Pediatric Ambulatory Anesthesia: Part 2—One Center's 15 Year Experience Improving Quality and Safety Outcomes

Pediatric Anesthesia, EarlyView.
ABSTRACT Introduction Pediatric ambulatory surgery has become the dominant model of surgical care in the United States, driven primarily by economic forces. There is variability in regional practice patterns, quality improvement cycles, and outcomes. Opportunity exists to overcome knowledge gaps and provide sustainable pathways of quality improvement ...
Jennifer L. Chiem, Elizabeth E. Hansen, Kayla Reece, Samuel M. Vanderhoek, Sanjay R. Parikh, Paul A. Merguerian, Lynn D. Martin   +6 more
wiley   +1 more source

Ketorolac Administration After Colorectal Surgery Increases Anastomotic Leak Rate: A Meta-Analysis and Systematic Review

Frontiers in Surgery, 2022
ObjectiveThis meta-analysis aimed to evaluate whether ketorolac administration is associated with an increased anastomotic leak rate after colorectal surgery.MethodsThe literature was searched using the Web of Science, Embase, and PubMed databases, and ...
Wen Chen, Jing Liu, Yongqiang Yang, Yanhong Ai, Yueting Yang   +4 more
doaj   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

PM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen, Nafis Eghrari, David Leong, Philip Chang, Jasmine Zheng, Amy Ng, Richard Wilson, Mary Vargo   +7 more
wiley   +1 more source

Effects of single and combination dosage regimens of ketorolac and dexmedetomidine on allodynia and nociception in rat model of osteoarthritis: an animal multi-group trial

BMC Anesthesiology
Introduction Ketorolac is a non-steroidal anti-inflammatory drug (NSAID), commonly used for acute pain relief. Dexmedetomidine is a highly selective alpha-2-adrenergic receptor agonists with an analgesic effect.
Saeed Mohammad Taheri, Mona Khoramjouy, Noushin Nikray, Narjes Mohammadzadeh, Sona Eslampour, Ehsan Firoozi, Sepehr Roozdar, Seyed Mohammadreza Hashemian, Mehrdad Faizi   +8 more
doaj   +1 more source