Results 51 to 60 of about 2,565 (186)

Mikroskaliges Tätowieren von Hydrogelen und Zellen: benzoxaborolbasierter Mikrokontaktdruck (µCP) auf glykolisierte Oberflächen

Angewandte Chemie, Volume 137, Issue 35, August 25, 2025.
Wir zeigen ein polymergestütztes Mikrokontaktdruckverfahren (µCP) zur Strukturierung glykosylierter Oberflächen. Als Tinte für die Oberflächenstrukturierung verwendeten wir ein Benzoboraxol‐Derivat. Mit dieser neuartigen Methode konnten wir Waferoberflächen mit Glykopolymerfilmen, oberflächen‐glykosylierten Polymermikropartikel sowie zelluläre ...
Nazim Pallab, Eric Sperlich, Matthias Schenderlein, Anne Krüger‐Genge, Jinyuan Li, Lukas Zeininger, Zdeněk Tošner, Mariusz Uchman, Martin Reifarth   +8 more
wiley   +1 more source

Update: Enzymatische Synthese für industrielle Anwendungen

Angewandte Chemie, Volume 137, Issue 27, July 1, 2025.
Die Biokatalyse hat sich zu einer nachhaltigen und wettbewerbsfähigen Alternative zur herkömmlichen chemischen Synthese entwickelt und ermöglicht die enzymbasierte Herstellung nicht nur von chemischen Grundstoffen, sondern auch von (nicht natürlichen) Aminosäuren, (seltenen) Zuckern und synthetischen Nukleotiden.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Volume 64, Issue 27, July 1, 2025.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Optimization of inulin extraction from Inula helenium L. using response surface methodology followed by its MALDI-TOF and TLC-FLD based characterization

Journal of Medicinal Plants, 2022
Background: Inulin, a prebiotic, is a mixture of linear chains β-2,1 fructans with a degree of polymerization (DP) of 2 to 60. Different DPs have various applications in the cosmetics, pharmaceutical, and food industries.
Mahdi Moridi Farimani, Elham Ahmadi, Hassan Rezadoost   +2 more
doaj  

Overexpression of Transketolase Relieves xylA Repression and Enhances Xylose Utilization in Saccharomyces cerevisiae During Mixed Sugar Fermentation

GCB Bioenergy, Volume 17, Issue 7, July 2025.
To overcome the bottleneck of inefficient xylose utilization in lignocellulosic bioethanol production, we constructed a recombinant Saccharomyces cerevisiae strain (INVSc‐xylA‐Xltr1p‐TKL1) by overexpressing the transketolase gene TKL1. This engineering strategy significantly enhanced xylose consumption by 33%, upregulated xylose isomerase (xylA ...
Si Xu, Wanli Cheng, Huanan Li, Jiashu Liu, Kexin Chen, Zhengbing Jiang   +5 more
wiley   +1 more source

A Biocatalytic Cascade for the Valorization of Sugars

ChemCatChem, Volume 17, Issue 12, June 23, 2025.
We report a one‐pot, three‐step biocatalytic cascade to synthesize trihydroxy‐piperidine and ‐azepane iminosugars directly from monosaccharides, employing transaminase (ATA) and galactose oxidase (GOase) enzymes. Abstract Biocatalytic cascades offer products of multistep synthesis without the use of protecting groups or isolation of intermediates. This
Kathryn Yeow, Aoife Martin, Jimmy Muldoon, Marianne Bore Haarr, Elaine O'Reilly   +4 more
wiley   +1 more source

<b>EFFECT OF GERMINATION ON OLIGOSACCHARIDE AND REDUCING SUGAR CONTENTS OF BRAZILIAN SOYBEAN CULTIVARS</b>

Alimentos e Nutrição, 2009
<p align="justify">ABSTRACT: Raffinose and stachyose levels decreased during germination in the Brazilian soybean (Glycine max. (L.) Merril) Cultivars IAC-5, IAC-8 GX and Foscarim GA, which are the most extensively produced cultivars in the Riberà ...
HUGO CANDIDO SILVA, GILBERTO LEITE BRAGA, MARIA DE LOURDES PIRES BIANCHI, ELIZEU ANTONIO ROSSI   +3 more
doaj  

The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism

Advanced Science, Volume 12, Issue 19, May 22, 2025.
Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang, Yi Xie, Shenglong Xia, Xinnuo Ge, Jiaying Li, Fang Liu, Fan Jia, Shengyao Wang, Qiao Zhou, Menghan Gao, Weihuan Fang, Chao Zheng   +11 more
wiley   +1 more source

Characteristic metabolite profile of 10 colorectal cancer-related bacteria

Frontiers in Oncology
BackgroundTumor metabolomics of colorectal cancer (CRC) is significantly different from normal tissues, due to nutrient deprivation, metabolite accumulation, acidity and hypoxia. Besides, gut microbiota has been confirmed to affect the progression of CRC.
Yongqiang Liu, Wangli Mei, Xinyan Huang, Xudong Yao, Cheng Kong, Cheng Kong, Yifan Chen   +6 more
doaj   +1 more source

Growth‐Coupled Evolutionary Pressure Improving Epimerases for D‐Allulose Biosynthesis Using a Biosensor‐Assisted In Vivo Selection Platform

Advanced Science
Fast screening strategies that enable high‐throughput evaluation and identification of desired variants from diversified enzyme libraries are crucial to tailoring biocatalysts for the synthesis of D‐allulose, which is currently limited by the poor ...
Chao Li, Xin Gao, Huimin Li, Tong Wang, Fuping Lu, Hui‐Min Qin   +5 more
doaj   +1 more source