Results 81 to 90 of about 43,609 (318)

Plasma metabolomics identifies signatures that distinguish heart failure with reduced and preserved ejection fraction

ESC Heart Failure, EarlyView.
Abstract Aims Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop phenotype‐specific approaches to treatment, distinguishing biomarkers are needed. The goal of this study was to utilize quantitative metabolomics on a large, diverse population to replicate and ...
Fawaz Naeem, Teresa C. Leone, Christopher Petucci, Clarissa Shoffler, Ravindra C. Kodihalli, Tiffany Hidalgo, Cheryl Tow‐Keogh, Jessica Mancuso, Iphigenia Tzameli, Donald Bennett, John D. Groarke, Rachel J. Roth Flach, Daniel J. Rader, Daniel P. Kelly   +13 more
wiley   +1 more source

Beta-Hydroxybutyric Acid Inhibits Renal Tubular Reabsorption via the AKT/DAB2/Megalin Signalling Pathway

Journal of Diabetes Research, 2022
Aim. Patients with diabetic ketosis often exhibit albuminuria. We previously found that acute hyperglycaemia can cause nephrotoxic injury. Here, we explored whether an excessive ketone body level causes kidney injury and the potential underlying ...
Minxia Zuo, Cheng Meng, Qian Song, Zhongai Gao, Xiao Cui, Jingyu Wang, Yongmei Li, Xiaochen Li, Chunyan Shan, Juhong Yang, Baocheng Chang   +10 more
doaj   +1 more source

Causal Relationship Between Various Vitamins and Different Diabetic Complications: A Mendelian Randomization Study. [PDF]

Food Sci Nutr
The potential causal relationships between six diabetic complications and four circulating vitamins in diabetics were explored through two‐sample Mendelian randomization analyses. ABSTRACT Epidemiological evidence regarding the association between vitamins and diabetic complications remains inconsistent.
Cai S, Man W, Liu W, Li B, He Z, Duan G.
europepmc   +2 more sources

The crosstalk between immune activation and metabolism in heart failure. A scientific statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
Abstract A better understanding of additional mechanisms of heart failure (HF) progression may allow a different and more complete phenotyping of the disease and identification of novel therapeutic targets. Persistent latent myocardial inflammation/immune activation in HF may represent an attempt to restore tissue homeostasis in the failing heart ...
Gabriele Fragasso, Davide Stolfo, Markus S. Anker, Antoni Bayes‐Genis, Ovidiu Chioncel, Stephane Heymans, Pardeep S. Jhund, Basil S. Lewis, Gary D. Lopaschuk, Lars H. Lund, Arantxa Gonzalez, Matteo Pagnesi, Gabriele Giacomo Schiattarella, Carlo Gabriele Tocchetti, Peter van der Meer, Sophie Van Linthout, Sven Wassmann, B. Daan Westenbrink, Marco Metra, Giuseppe M.C. Rosano, Gianluigi Savarese   +20 more
wiley   +1 more source

Prevalence and clinical characteristics of lower limb atherosclerotic lesions in newly diagnosed patients with ketosis-onset diabetes: a cross-sectional study [PDF]

, 2014
BACKGROUND: The clinical features of atherosclerotic lesions in ketosis-onset diabetes are largely absent. We aimed to compare the characteristics of lower limb atherosclerotic lesions among type 1, ketosis-onset and non-ketotic type 2 diabetes. METHODS:
Cui-Chun Zhao, Fang Liu, Jun-Xi Lu, Lian-Xi Li, Mei-Fang Li, Rong Zhang, Wei-Jing Zhao, Wei-Ping Jia, Yin-Fang Tu, Ying Ren, Yu-Qian Bao   +10 more
core   +2 more sources

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Ketosis and its role in Bos taurus reproductive impairment

RUDN Journal of Agronomy and Animal Industries, 2020
The analysis of relevant and significant scientific research on the physiological and biochemical aspects of ketosis, and the main mechanisms of influence on reproductive function in this metabolic pathology is presented. Strengthening breeding potential
Gennady V. Shiryaev, Tatyana I. Stanislavovich, Vladimir P. Politov   +2 more
doaj   +1 more source

Prevalence of ketosis in dairy cows in milk shed areas of Odisha state, India [PDF]

Veterinary World, 2016
Aim: The present study was conducted to ascertain the prevalence of ketosis in dairy cows in dairy herds, milksheds, and mixed population of milk cows selected randomly in milkshed areas of Odisha state, India.
Sangram Biswal, Dhruba Charan Nayak, Kautuk Kumar Sardar   +2 more
doaj   +1 more source

[KETOSIS].

Liječnički vjesnik, 2020
This datasheet on ketosis covers Identity, Overview, Distribution, Hosts/Species Affected, Diagnosis, Pathology, Impacts, Prevention/Control, Further Information.
V. Mikulčić
semanticscholar   +1 more source

Post‐exercise ketosis. [PDF]

The Journal of Physiology, 1980
1. The effect of exercise on blood ketone body concentrations was studied in trained athletes and in sedentary subjects pedalling a bicycle ergometer. 2. Although the untrained subjects had higher heart rates and blood lactate concentrations at the same work load as the athletes, neither group developed ketonaemia even after intense or prolonged ...
A W Sloan, J H Koeslag, Timothy D. Noakes   +2 more
openaire   +3 more sources