Beyond lipids: Systemic effects of lipoprotein apheresis
Transfusion, EarlyView.
Menatalla Nadim, Yamac Akgun
wiley +1 more source
Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma
Advanced Science, Volume 13, Issue 3, 14 January 2026.IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang +16 more
wiley +1 more source
Characterization of a quantitative method to measure free proprotein convertase subtilisin/kexin type 9 in human serum [PDF]
, 2014 Alexander Colbert +5 more
openalex +1 more source
NUSAP1 Recruits DAXX to Suppress HIF‐Driven Triple‐Negative Breast Cancer Progression
Advanced Science, Volume 13, Issue 5, 27 January 2026.A double‐negative feedback loop is identified in TNBC where NUSAP1 bridges HIF and DAXX via its microtubule‐associated domain (MAD) to recruit SETDB1, repressing HIF transcriptional activity by depositing the H3K9me3 repressive mark on HIF target genes, while HIF itself suppresses NUSAP1.
Yating Du +14 more
wiley +1 more source
Effects of proprotein convertase subtilisin/kexin type-9 inhibitors on fatty liver
, 2020 Muhammad Shafiq +4 more
openalex +1 more source
Proprotein convertase subtilisin/kexin type 9 levels and aortic valve calcification: A prospective, cross sectional study [PDF]
, 2016 Wenguang Wang +11 more
openalex +1 more source
Butanolic Extract of Noni Inhibits Proliferation, Inflammation, and Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Expression in Cultured Smooth Muscle Cells [PDF]
, 2020 Takanori Matsui +5 more
openalex +1 more source
Ramadan Intermittent Fasting Is Associated with Changes in Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Metabolically Healthy Obese Subjects [PDF]
, 2022 Hayder Hasan +5 more
openalex +1 more source
Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.Punica granatum peel extract is rich in phenolic compounds, exhibits strong antioxidant activity, and modulates the expression of PCSK9 and LDL receptors. Collectively, these findings suggest a potential cardioprotective effect of the extract. ABSTRACT Lipoprotein metabolism is regulated by several key proteins, notably proprotein convertase subtilisin/
Raja Chaaba +9 more
wiley +1 more source
Vascular Health and Risk Management, 2017 Alberico Luigi Catapano,1,2 Angela Pirillo,1,2 Giuseppe Danilo Norata1,3,4 1Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 2IRCCS Multimedica Hospital, Sesto San Giovanni, 3Center for the Study of ...
Catapano AL, Pirillo A, Norata GD
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