Results 61 to 70 of about 23,218 (270)

Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis

Journal of Lipid Research, 2007
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protease that regulates low density lipoprotein receptor (LDLR) protein levels. The mechanisms of this action, however, remain to be defined.
Yue-Wei Qian, Robert J. Schmidt, Youyan Zhang, Shaoyou Chu, Aimin Lin, He Wang, Xiliang Wang, Thomas P. Beyer, William R. Bensch, Weiming Li, Mariam E. Ehsani, Deshun Lu, Robert J. Konrad, Patrick I. Eacho, David E. Moller, Sotirios K. Karathanasis, Guoqing Cao   +16 more
doaj   +1 more source

Incorporating crystalline smart materials to fabricate 4D printed photomechanical actuators with photovoltaic performance

Smart Molecules, EarlyView.
A versatile 4D printed approach was developed to fabricate complex and refined photomechanical actuators using crystalline materials, including molecular crystals and covalent organic frameworks. The prepared smart actuators exhibited outstanding photomechanical and photovoltaic performance.
Yujie Liu, Jinjin Liu, Liqin Hao, En Lin, Jiaxi Wang, Tonghai Wang, Shubo Geng, Peng Cheng, Zhenjie Zhang   +8 more
wiley   +1 more source

Perkembangan Implikasi Biologi dan Klinis Proprotein Convertase Subtilisin-Kexin 9

Majalah Kardiologi Indonesia, 2017
Pada tahun 2003 Proprotein Convertase Subtilisin-Kexin 9 (PCSK9) berhasil diidentifikasi.1 PCSK9 berfungsi meningkatkan kadar LDL Cholesterol (LDL-C) melalui degradasi LDL Receptor (LDLR).2 Penemuan PCSK9 telah merevolusi serta merupakan perkembangan ...
doaj   +1 more source

Electronic health records improve the diagnosis and prognosis of pulmonary fungal infections in lung cancer patients

VIEW, EarlyView.
Pulmonary fungal infections are life‐threatening complications in lung cancer patients, posing significant challenges in clinical management. To address this, we developed machine learning tools that translate routine electronic health record data into actionable insights for diagnosing infections and assessing prognosis.
Hongwei Meng, Jiayun Yang, Shouzhi Yang, Ayizekeranmu Yiming, Wenjun Yu, Yuewei Zhao, Chunmeng Ding, Kexin Meng, Si Gao, Yang Li, Nan Dan, Dandan Feng, Yunhua Xu, Lin Huang, Yongxia Qiao   +14 more
wiley   +1 more source

Research on the Factors Analysis and Strategies of LVMH’s Profitability [PDF]

SHS Web of Conferences
Moet Hennessy Louis Vuitton (LVMH）has been expanding its territory in the group through mergers and acquisitions. The success rate of the group’s acquisition is very high, and through excellent management and operation, many unknown small brands can ...
Wang Kexin
doaj   +1 more source

PSMA PET‐directed radiotherapy for prostate cancer: From precision planning to future innovations

VIEW, EarlyView.
Prostate‐specific membrane antigen (PSMA) positron emission tomography (PET) imaging enables highly sensitive detection of prostate cancer recurrence and precise lesion mapping. This review summarizes current evidence and emerging applications of PSMA PET in radiotherapy, including diagnostic staging, target delineation, adaptive planning, and outcome ...
Wenpeng Huang, Jessica C. Hsu, Ruobing Li, Kexin Lan, Xin Qi, Yuchun Wei, Weibo Cai, Hongzhen Li   +7 more
wiley   +1 more source

The history of proprotein convertase subtilisin kexin-9 inhibitors and their role in the treatment of cardiovascular disease [PDF]

, 2020
Eun Ji Kim, Anthony S. Wierzbicki
openalex   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Clinical studies of monoclonal antibodies against the proprotein convertase subtilisin / kexin type 9

Атеросклероз, 2015
The review presents the current data of scientific literature about different phases of clinical trials of monoclonal antibodies against the proprotein convertase subtilisin/kexin type 9 (PCSK9). The results of completed clinical trials and the review of
K. S. Astrakova, Yu. I. Ragino, E. V. Shakhtshneider, M. I. Voevoda   +3 more
doaj  

Significance of Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) for the Monitoring of Treatment Response to Cyclosporine in Patients with Psoriasis [PDF]

, 2023
Aleksandra Frątczak, Bartosz Miziołek, Agnieszka Łupicka‐Słowik, Marcin Sieńczyk, Karina Polak, Beata Bergler‐Czop   +5 more
openalex   +1 more source