Results 71 to 80 of about 48,363 (248)
Natriuretic Peptides in the Cardiovascular System. Multifaceted Roles in Physiology, Pathology and Therapeutics [PDF]
, 2019 The natriuretic peptides (NPs) family includes a class of hormones and their receptors needed for the physiological control of cardiovascular functions. The discovery of NPs provided a fundamental contribution into our understanding of the physiological ...
Rubattu, Speranza, Volpe, Massimo
core +1 more source
iNew Medicine, EarlyView.ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source
The State of Black Immigrants Part I: A Statistical Portrait of Black Immigrants in the United States [PDF]
, 2016 The last four decades have represented a period of significant demographic change in the United States. Now more than ever, Black immigrants compose a significant percentage of both immigrant and Black populations in the U.S. overall.
Juliana MorganTrostle, Kexin Zheng
core
Vascular Calcification: Mechanisms, Models, and Therapies
iNew Medicine, EarlyView.ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Optimization and Abstraction: A Synergistic Approach for Analyzing Neural Network Robustness
, 2019 In recent years, the notion of local robustness (or robustness for short) has emerged as a desirable property of deep neural networks. Intuitively, robustness means that small perturbations to an input do not cause the network to perform ...
Bastani Osbert +13 more
core +1 more source
Demazure descent and representations of reductive groups [PDF]
, 2014 We introduce the notion of Demazure descent data on a triangulated category C and define the descent category for such data. We illustrate the definition by our basic example. Let G be a reductive algebraic group with a Borel subgroup B.
Arkhipov, Sergey, Kanstrup, Tina
core +3 more sources
Interdisciplinary Medicine, EarlyView.A CRISPR/Cas12a‐powered dendritic DNA nanostructure is assembled to create confined enzymatic microdomains, enabling ultrasensitive detection. Integrated into a paper‐based origami biosensor, it allows equipment‐free on‐site quantification of acidogenic pathogens for the early diagnosis of dental caries.
Yuan Zhang +4 more
wiley +1 more source
Evaluation of adropin indices and PCSK9 in non-diabetic men with severe obstructive sleep apnea
Türk Biyokimya DergisiWe aimed to investigate the relationship among proprotein convertase subtilisin/kexin type 9 (PCSK9), adropin levels, inflammation, and sleep variables in non-diabetic males with severe obstructive sleep apnea (OSA).
Deniz Levent +4 more
doaj +1 more source
Perkembangan Implikasi Biologi dan Klinis Proprotein Convertase Subtilisin-Kexin 9
Majalah Kardiologi Indonesia, 2017 Pada tahun 2003 Proprotein Convertase Subtilisin-Kexin 9 (PCSK9) berhasil diidentifikasi.1 PCSK9 berfungsi meningkatkan kadar LDL Cholesterol (LDL-C) melalui degradasi LDL Receptor (LDLR).2 Penemuan PCSK9 telah merevolusi serta merupakan perkembangan ...
doaj +1 more source
Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis
Journal of Lipid Research, 2007 Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protease that regulates low density lipoprotein receptor (LDLR) protein levels. The mechanisms of this action, however, remain to be defined.
Yue-Wei Qian +16 more
doaj +1 more source