Results 51 to 60 of about 255,138 (288)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Adapting the BIKE Key Encapsulation Mechanism to Memory-Constrained IoT Devices

open access: yesCryptography
Post-quantum cryptography represents one of the most promising areas of modern cryptography. The development in this discipline significantly accelerated after it became of interest to the National Institute of Standards and Technology (NIST). One of the
Dušan Čatloch   +2 more
doaj   +1 more source

Highly Vectorized SIKE for AVX-512

open access: yesTransactions on Cryptographic Hardware and Embedded Systems, 2022
It is generally accepted that a large-scale quantum computer would be capable to break any public-key cryptosystem used today, thereby posing a serious threat to the security of the Internet’s public-key infrastructure.
Hao Cheng   +3 more
doaj   +1 more source

KEM-based Authenticated Key Exchange Protocol on Lattice [PDF]

open access: yesJisuanji gongcheng, 2020
To solve the problem that existing Authenticated Key Exchange(AKE) protocols have high computational complexity and cannot resist quantum attacks,this paper proposes an AKE protocol based on R-LWE problem on lattice.The KEM scheme constructed based on R ...
ZHAO Zongqu, HUANG Lijuan, FAN Tao, MA Shaoti
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Post-Quantum Wireless-Based Key Encapsulation Mechanism via CRYSTALS-Kyber for Resource-Constrained Devices

open access: yesIEEE Access
We consider the problem of adapting a Post-Quantum cryptosystem to be used in resource-constrained devices, such as those typically used in Device-to-Device and Internet of Things systems.
M. A. Gonzalez de la Torre   +3 more
doaj   +1 more source

High-speed SABER Key Encapsulation Mechanism in 65nm CMOS [PDF]

open access: yes, 2022
Quantum computers will break cryptographic primitives that are based on integer factorization and discrete logarithm problems. SABER is a key agreement scheme based on the Learning With Rounding problem that is quantum-safe, i.e., resistant to quantum ...
Malik Imran   +4 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

A practical key-recovery attack on LWE-based key- encapsulation mechanism schemes using Rowhammer [PDF]

open access: yes, 2023
Physical attacks are serious threats to cryptosystems deployed in the real world. In this work, we propose a microarchitectural end-to-end attack methodology on generic lattice-based post-quantum key encapsulation mechanisms to recover the long-term ...
Suparna Kundu   +4 more
core   +2 more sources

Certificateless Deniable Authenticated Encryption for Location-Based Privacy Protection

open access: yesIEEE Access, 2019
Deniable authenticated encryption (DAE) is a cryptographic primitive that supports data confidentiality with deniable authentication in an efficient manner. The DAE plays a significant role in location-based service systems for privacy protection.
Guanhua Chen   +6 more
doaj   +1 more source

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