Encapsulation-free controlled release: Electrostatic adsorption eliminates the need for protein encapsulation in PLGA nanoparticles [PDF]
Encapsulation of therapeutic molecules within polymer particles is a well-established method for achieving controlled release, yet challenges such as low loading, poor encapsulation efficiency, and loss of protein activity limit clinical translation ...
Malgosia M. Pakulska (7161425) +6 more
core +2 more sources
Certificateless Deniable Authenticated Encryption for Location-Based Privacy Protection
Deniable authenticated encryption (DAE) is a cryptographic primitive that supports data confidentiality with deniable authentication in an efficient manner. The DAE plays a significant role in location-based service systems for privacy protection.
Guanhua Chen +6 more
doaj +1 more source
A provably masked implementation of BIKE Key Encapsulation Mechanism
BIKE is a post-quantum key encapsulation mechanism (KEM) selected for the 4th round of the NIST's standardization campaign. It relies on the hardness of the syndrome decoding problem for quasi-cyclic codes and on the indistinguishability of the public key from a random element, and provides the most competitive performance among round 4 candidates ...
Loïc Demange, Mélissa Rossi
openaire +2 more sources
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Public Key Protocols from Twisted-Skew Group Rings
This article studies some algebraic structures known as twisted-skew group rings in the context of public key cryptography. We first present some background related to these structures to then specifically introduce particular twisted-skew group rings ...
Javier de la Cruz +3 more
doaj +1 more source
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Secure Cryptographic Key Encapsulation and Recovery Scheme in Noisy Network Conditions
In this study, we present the Response-Based Key Encapsulation Mechanism (R-KEM), an ephemeral key encapsulation and recovery scheme tailored for cryptographic systems in high-noise, high-jamming network environments.
Dina Ghanai Miandoab +5 more
doaj +1 more source
Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad +22 more
wiley +1 more source
A Concrete LIP-Based KEM With Simple Lattices
Recent developments have been made in the construction of cryptosystems with security based on the hardness of the lattice isomorphism problem (LIP). Due to lattice conjectures, one may expect in the future that breaking such schemes is computationally ...
Gustavo de Castro Biage +4 more
doaj +1 more source

