Results 121 to 130 of about 427,417 (300)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Two-party Quantum Key Agreement Protocol Based on GHZ States

open access: yes工程科学与技术, 2016
:In order to solve the problem that the multi-particle joint measurements are difficult to implement with the existing technology in the quantum key agreement protocols based on multi-particle entangled states , a new two-party quantum key agreement ...
He Ye-feng
doaj  

A Communication-efficient and Fault-tolerant Conference-key Agreement Protocol with Forward Secrecy

open access: yes, 2012
[[abstract]]A conference-key establishment protocol allows participants to construct a common session key that is used to encrypt/decrypt transmitted messages among the participants over an open channel.
Tseng, Yuh-Min
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Inter-Domain Identity-based Authenticated Key Agreement Protocol from the Weil Pairing

open access: yes, 2007
當溝通雙方分處於不同領域 (domain) ,而想建立共享金鑰來進行祕密通訊時,就需要一個跨領域的金鑰合議協定 (key agreement protocol) 。近年來,很多身份基礎 (identity-based) 的附驗證 (authenticated) 金鑰合議協定被提出來。絕大多數的研究在解決此類通訊協定效率問題時,皆假設溝通的雙方處於同一個領域;例如:同一間公司的雇員。也就是說,在身份基礎的架構 (identity-based scheme) 下,溝通的雙方必須向同一個被信任的管理者 ...
蔡宏彬, Tsai, Hong-Bin
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

A secure identity-based key agreement protocol without key-escrow

open access: yes, 2017
In the past decade, pairing-based schemes have been proposed extensively for the cryptographic primitives including key agreement. However, recently researchers have shown an increased interest in Pairing-Free cryptography because of high computational ...
Razak, S. A.   +3 more
core  

Efficient Identity-Based and Authenticated Key Agreement Protocol [PDF]

open access: yes, 2005
Several identity based and authenticated key agreement protocols have been proposed in recent years and all of them have been shown to be non-secure. It remains an open question to design secure identity based and authenticated key agreement protocols ...
Yongge Wang
core  

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