Results 181 to 190 of about 427,417 (300)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Extending Joux\u27s Protocol to Multi Party Key Agreement
, 2003 We present a secure unauthenticated as well as an authenticated multi party key agreement protocol. The unauthenticated version of our protocol uses ternary trees and is based on bilinear maps and Joux\u27s three party protocol.
Palash Sarkar, Rana Barua, Ratna Dutta
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Analysis of key agreement protocols
, 2006 NORSK: Masteroppgaven tar for seg noen av de siste foreslåtte protokollene for nøkkel-utveksling. Ettersom de er så nye, har de ikke gjennomgått en detaljert analyse, og kan derfor inneholde sikkerhetshull. Sikkerhet i protokollene er viktig, ettersom de er ansvarlig for integriteten og konfidensialiteten til all kommunikasjon fra det øyeblikket de tas
openaire +1 more source
Improved Yen-Joye's Authenticated Multiple-key Agreement Protocol
, 2010 [[abstract]]An authenticated multiple-key agreement protocol is proposed.
Min-Shiang Hwang; Chih-Wei Lin;Cheng-Chi Lee
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Hierarchical multi-device authentication and key agreement protocol for industrial IoT
网络与信息安全学报A secure authentication key negotiation protocol was considered to be of vital importance for ensuring the legitimacy of device nodes and managers, as well as the confidentiality of data in the Industrial Internet of Things.
WU Yi, FENG Tao, LIU Chunyan, SU Chunhua
doaj