Results 81 to 90 of about 6,647,574 (329)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Practices in Integrating Workplace Learning into Upper Secondary Education

open access: yesSocial Sciences
In recent years, Estonian employers, upper secondary schools, and other stakeholders have devised various new collaborative measures to effectively integrate workplace learning (WPL) and school education.
Birgit Peterson   +2 more
doaj   +1 more source

POLICIES AND GOUVERNANCE IN EDUCATION [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2019
Using the concepts of profitability and efficiency, we have tried to provide an overview of educational outcomes with the efforts, capital and assets used as well as management solutions to ensure the best rate of integration of education resources and
ADINA CLAUDIA NEAMȚU, LIVIU NEAMȚU
doaj  

Competitve Growth: the Development of Key Competences and Corporate Venturing

open access: yesУправленческие науки, 2016
The article is based on the hypothesis that formation, keeping and development of organization’s key competences each reflecting the competitive advantage is the most important condition for business’ competitive growth.
A. I. Kashirin   +4 more
doaj   +1 more source

Effective Management of Urban Affairs by Promoting Core Competencies in Zahedan Municipality [PDF]

open access: yesپژوهش‌های مدیریت عمومی, 2019
Extended Abstract Abstract The most important and most important asset of any organization is its human resources. Quality and capability of human resources is the most important factor in the survival of the organization.
Masoume Zaree kaseb, AminReza Kamalian
doaj   +1 more source

Визначення ключових компетентностей майбутніх вчителів у країнах Європи [PDF]

open access: yes, 2008
У статті розглядається провідне педагогічне поняття “ключові компетентності вчителів”. У змісті наукової розвідки на основі європейських джерел та вітчизняних публікацій розкриваються загальні підходи до визначення ключових компетентностей, що ними ...
П'янковська , І. В. (I. Piankovska)
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Describing Papers and Reviewers' Competences by Taxonomy of Keywords

open access: yes, 2012
This article focuses on the importance of the precise calculation of similarity factors between papers and reviewers for performing a fair and accurate automatic assignment of reviewers to papers. It suggests that papers and reviewers' competences should
Kalmukov, Yordan
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

STRENGTHENING THE COMPETENCE ORIENTATION OF THE NATURAL SCIENCE SCHOOL EDUCATION CONTENT AS CONDITION OF ALL-ROUND DEVELOPMENT OF A PERSONALITY

open access: yesEducation: Modern Discourses, 2019
The article addresses an issue of structuring the natural science school education content and substantiates the trends of its modernization under orientation at the all-round development of a personality.
Оleg Topuzov, Mykola Golovko
doaj   +1 more source

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