Results 161 to 170 of about 917,346 (268)

Advances in GelMA Hydrogel-Enabled Angiogenic-Osteogenic Coupling: From Structural Programming to Exogenous Cue Synergy. [PDF]

J Funct Biomater
Hu C, Zhang M, Jiang H, Qu Y, Meng Q, Tian J, Zhang H, Yang Z, Lin Z, Xing B, Zhang P.   +10 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Engineering spherical nucleic acids for precision cancer therapy: design strategies and medical applications. [PDF]

Theranostics
Wang Y, Wu W, Yao F.
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Transitioning from Episodic Cardiac Missions to Sustainable National Cardiac Surgery Services in Papua New Guinea: A Mixed-Methods Programme Evaluation. [PDF]

Ann Glob Health
Lizwan M, Zhu L, Tapaua N, Zeng A, Ng O, Chua KC, Chua YL.   +6 more
europepmc   +1 more source

PD-1 and LAG-3 dual blockade: emerging mechanisms and potential therapeutic prospects in cancer

Cancer Biology & Medicine
Xiangyu Qiu, Zhaoan Yu, Xiaoqing Lu, Xin Jin, Jinrong Zhu, Rongxin Zhang   +5 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Balancing Trade-Offs in Patient and Public Involvement and Engagement in Rapid Evaluation: Reflections and Lessons. [PDF]

Health Expect
Ng PL, Mehta R, Ramsay AIG, Fulop NJ, Shand J.   +4 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Spatiotemporal precision interventions for cardiac repair and regenerative therapy. [PDF]

Exp Mol Med
Ting MH, Zhang H, Liu S, Wang P, Li H, Zhang W, Ge J, Zhang N.   +7 more
europepmc   +1 more source