Results 261 to 270 of about 2,747,705 (306)
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Keys to Delivery: An Interview with Hildegard Büning
Human Gene Therapy, 2021Editor's note: Hildegard Buning is one of the leading gene therapy researchers in Europe. She has been a key figure in the field of adeno-associated virus research and capsid engineering for some two decades, and is currently deputy director of the Institute of Experimental Hematology at Hannover Medical School in Germany.
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Late‐onset gestational diabetes: Could earlier delivery be the key?
BJOG: An International Journal of Obstetrics & Gynaecology, 2022Linked article: This is a mini commentary on Matthew Cauldwell et al., pp. 2176–2183 in this issue.
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Clinical Protocols Are Key to Quality Health Care Delivery
International Journal of Health Care Quality Assurance, 1994The use of clinical protocols allows health care providers to offer appropriate diagnostic treatment and care services to patients, variance reports to purchasers and quality training to clinical staff. Such protocols provide a locally agreed standard to which clinicians and the organization can work and against which they can be audited.
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Non-Viral Nucleic Acid Delivery: Key Challenges and Future Directions
Current Drug Delivery, 2011Gene therapy holds the promise of correcting a genetic defect. It can be achieved with the introduction of a normal wild-type transgene into specific cells of the patient where the endogenous gene is underexpressing or by the introduction of a therapeutic agent, such as, antisense oligonucleotides (AON) or small interfering RNA (siRNA) to inhibit ...
Mahmoud, Elsabahy +2 more
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Targeted Blood-to-Brain Drug Delivery – 10 Key Development Criteria
Current Pharmaceutical Biotechnology, 2012Drug delivery to the brain remains challenging due to the presence of the blood-brain barrier. In this review, 10 key development criteria are presented that are important for successful drug development to treat CNS diseases by targeted drug delivery systems.
Pieter J, Gaillard +3 more
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How it's done: Keys to implementation of delivery system reform
Healthcare, 2013The vision of Obamacare - including the expansion of health care coverage to millions more Americans - rests in no small part on the reduction of health care waste and the spread of cheaper, more sustainable models of health care delivery. Though this will require thoughtful policy, powerful payment incentives and innovative new models of care delivery,
C Joseph, McCannon, Aaron, McKethan
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ZETA POTENTIAL: A KEY FACTOR IN DRUG DELIVERY
This review article deals with measurement and applications of zeta potential, zeta potential in pharmaceutical formulation, Role of zeta potential in stability, material design and preparation. Zeta potential (ζ) is a measure of the magnitude of the repulsion or attraction between particles.Kalpana Devi* +4 more
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Controlled biodegradability of polymers — a key to drug delivery systems
Biomaterials, 1984By combining oligopeptide sequences with synthetic polymeric chains, carriers of drug models can be prepared. The drug model (p-nitroaniline) is cleaved from the carrier in the lysosomal compartment of the cell. By changing the length and structure of the oligopeptide sequence, it is possible to regulate the rate of cleavage of drug model by individual
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Planning for post‐pandemic cancer care delivery: Recovery or opportunity for redesign?
Ca-A Cancer Journal for Clinicians, 2021Pelin Cinar +2 more
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What Are the Key Targeted Delivery Technologies of siRNA Now?
2010Whilst significant advances have been made in the delivery of nucleic acids to mammalian cells, most of the used strategies do not distinguish between normal and cancer cells. The same challenge is also facing radioactive- and chemo-therapies which are highly toxic and poorly tolerated due to limited tumor specificity.
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