Results 271 to 280 of about 999,964 (314)

Controlled biodegradability of polymers — a key to drug delivery systems

Biomaterials, 1984
By combining oligopeptide sequences with synthetic polymeric chains, carriers of drug models can be prepared. The drug model (p-nitroaniline) is cleaved from the carrier in the lysosomal compartment of the cell. By changing the length and structure of the oligopeptide sequence, it is possible to regulate the rate of cleavage of drug model by individual
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Transgene Design and Delivery into the Mouse Genome: Keys to Success

2009
Mouse transgenesis by pronuclear injection generates random integration events resulting in variable overexpression efficiency. This chapter will outline current strategies for improved transgene design (using plasmids or bacterial artificial chromosomes) and delivery to the mouse genome.
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What Are the Key Targeted Delivery Technologies of siRNA Now?

2010
Whilst significant advances have been made in the delivery of nucleic acids to mammalian cells, most of the used strategies do not distinguish between normal and cancer cells. The same challenge is also facing radioactive- and chemo-therapies which are highly toxic and poorly tolerated due to limited tumor specificity.
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Gene Delivery the Key to Gene Therapy: the Case for Foamy Viruses

Therapeutic Delivery, 2011
"There have been rare cases of zoonotic transmission of foamy virus from monkeys to humans, but despite keeping these cases under close scrutiny for years no pathology has ever been detected...".
Otto, Erlwein, Myra, McClure
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Planning for post‐pandemic cancer care delivery: Recovery or opportunity for redesign?

Ca-A Cancer Journal for Clinicians, 2021
Pelin Cinar, Daniela A Bota, Kathryn A Gold   +2 more
exaly  

Silica key to drug delivery

Nano Today, 2006
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Drug delivery to the central nervous system

Nature Reviews Materials, 2021
Elizabeth Nance, Suzie H Pun, Drew L Sellers   +2 more
exaly  

Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs

Nature Reviews Materials, 2023
Sean A Dilliard, Daniel J Siegwart, Siegwart Daniel J   +2 more
exaly  

Phytomedicine and functional foods: Keys to sustainable healthcare delivery

Journal of Food Biochemistry, 2021
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Lipid nanoparticles for mRNA delivery

Nature Reviews Materials, 2021
Xucheng Hou, Tal Zaks, Robert Langer
exaly