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Key issues in non-viral gene delivery
Advanced Drug Delivery Reviews, 1998The future of non-viral gene therapy depends on a detailed understanding of the barriers to delivery of polynucleotides. These include physicomechanical barriers, which limit the design of delivery devices, physicochemical barriers that influence self-assembly of colloidal particulate formulations, and biological barriers that compromise delivery of ...
C W, Pouton, L W, Seymour
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Keys to Delivery: An Interview with Hildegard Büning
Human Gene Therapy, 2021Editor's note: Hildegard Büning is one of the leading gene therapy researchers in Europe. She has been a key figure in the field of adeno-associated virus research and capsid engineering for some two decades, and is currently deputy director of the Institute of Experimental Hematology at ...
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Drug delivery to mitochondria: the key to mitochondrial medicine
Advanced Drug Delivery Reviews, 2000The major function of mitochondria in human cells is to provide ATP by oxidative phosphorylation. However, mitochondria have many other roles including the modulation of intracellular calcium concentration and the regulation of apoptotic cell death.
M P, Murphy, R A, Smith
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Key Concepts in Healthcare Delivery
2017This chapter examines several key concepts in healthcare within an African context. The concepts include health, access to health, UHC and health systems. This chapter starts with the concept of “health,” the definition of which has been a recent subject of contention.
Jimoh Amzat, Oliver Razum
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Key Issues in the Delivery of Peptides and Proteins
1986During the workshop the delegates were assigned to small syndicate groups that met to discuss two assigned topics that represented key issues in the delivery of peptides and proteins. Each syndicate reported on their deliberations at the end of the meeting and this final chapter is based largely on these reports.
E. Tomlinson, S. S. Davis, L. Illum
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Clinical Protocols Are Key to Quality Health Care Delivery
International Journal of Health Care Quality Assurance, 1994The use of clinical protocols allows health care providers to offer appropriate diagnostic treatment and care services to patients, variance reports to purchasers and quality training to clinical staff. Such protocols provide a locally agreed standard to which clinicians and the organization can work and against which they can be audited.
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Key Processes in the Building Delivery of Green Hospitals
Construction Research Congress 2009, 2009The healthcare industry is one of the largest and most significant built environment markets today with over 120,000 buildings in the United States. Moreover, in the next 15 years, an estimated $300 billion will be spent on hospital construction across the United States.
Elena Enache-Pommer, Michael Horman
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Key to Delivery: The (Epi-)genome Editing Vector Toolbox
2018Curing a genetic disease by repairing the underlying genetic defect is a fascinating concept that has been addressed so far by gene compensation therapy. For this, a functional copy of the gene in question together with elements controlling its expression is produced as a vector and introduced ex vivo into the patient's own cells that subsequently are ...
Sabrina, Just, Hildegard, Büning
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Access Control with Individual Key Delivery in ICN
2022 IEEE International Symposium on Local and Metropolitan Area Networks (LANMAN), 2022Yuma Fukagawa, Noriaki Kamiyama
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Targeted delivery as key for the success of small osteoinductive molecules
Advanced Drug Delivery Reviews, 2015Molecules such as growth factors, peptides and small molecules can guide cellular behavior and are thus important for tissue engineering. They are rapidly emerging as promising compounds for the regeneration of tissues of the musculoskeletal system. Growth factors have disadvantages such as high cost, short half-life, supraphysiological amounts needed,
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