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Keys to Delivery: An Interview with Hildegard Büning
Human Gene Therapy, 2021Editor's note: Hildegard Büning is one of the leading gene therapy researchers in Europe. She has been a key figure in the field of adeno-associated virus research and capsid engineering for some two decades, and is currently deputy director of the Institute of Experimental Hematology at ...
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Overview of Quantum Key Distribution Network Key-Delivery Specifications
2025 International Conference on Quantum Communications, Networking, and Computing (QCNC)Quantum Key Distribution (QKD), a secret key agreement primitive, makes possible long-awaited real-world Information-Theoretical Security (ITS). In the last twenty years, the development of QKD-based networks that deliver ITS keys to distant parties has been a focus of the academic and industry sectors.
Mehic M. +5 more
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Key Issues in the Delivery of Peptides and Proteins
1986During the workshop the delegates were assigned to small syndicate groups that met to discuss two assigned topics that represented key issues in the delivery of peptides and proteins. Each syndicate reported on their deliberations at the end of the meeting and this final chapter is based largely on these reports.
E. Tomlinson, S. S. Davis, L. Illum
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Key to Delivery: The (Epi-)genome Editing Vector Toolbox
2018Curing a genetic disease by repairing the underlying genetic defect is a fascinating concept that has been addressed so far by gene compensation therapy. For this, a functional copy of the gene in question together with elements controlling its expression is produced as a vector and introduced ex vivo into the patient's own cells that subsequently are ...
Sabrina, Just, Hildegard, Büning
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Access Control with Individual Key Delivery in ICN
2022 IEEE International Symposium on Local and Metropolitan Area Networks (LANMAN), 2022Yuma Fukagawa, Noriaki Kamiyama
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Targeted delivery as key for the success of small osteoinductive molecules
Advanced Drug Delivery Reviews, 2015Molecules such as growth factors, peptides and small molecules can guide cellular behavior and are thus important for tissue engineering. They are rapidly emerging as promising compounds for the regeneration of tissues of the musculoskeletal system. Growth factors have disadvantages such as high cost, short half-life, supraphysiological amounts needed,
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Controlled biodegradability of polymers — a key to drug delivery systems
Biomaterials, 1984By combining oligopeptide sequences with synthetic polymeric chains, carriers of drug models can be prepared. The drug model (p-nitroaniline) is cleaved from the carrier in the lysosomal compartment of the cell. By changing the length and structure of the oligopeptide sequence, it is possible to regulate the rate of cleavage of drug model by individual
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Clinical Protocols Are Key to Quality Health Care Delivery
International Journal of Health Care Quality Assurance, 1994The use of clinical protocols allows health care providers to offer appropriate diagnostic treatment and care services to patients, variance reports to purchasers and quality training to clinical staff. Such protocols provide a locally agreed standard to which clinicians and the organization can work and against which they can be audited.
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Transgene Design and Delivery into the Mouse Genome: Keys to Success
2009Mouse transgenesis by pronuclear injection generates random integration events resulting in variable overexpression efficiency. This chapter will outline current strategies for improved transgene design (using plasmids or bacterial artificial chromosomes) and delivery to the mouse genome.
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What Are the Key Targeted Delivery Technologies of siRNA Now?
2010Whilst significant advances have been made in the delivery of nucleic acids to mammalian cells, most of the used strategies do not distinguish between normal and cancer cells. The same challenge is also facing radioactive- and chemo-therapies which are highly toxic and poorly tolerated due to limited tumor specificity.
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