Results 1 to 10 of about 9,159 (257)
Transdermal Delivery of Drugs with Microneedles—Potential and Challenges
Pharmaceutics, 2015 Transdermal drug delivery offers a number of advantages including improved patient compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect.
Kevin Ita
exaly +3 more sources
Versatile Ice Microneedles for Transdermal Delivery of Diverse Actives
Advanced Science, 2021 Microneedles are regarded as an emerging and promising transdermal drug delivery strategy. Great efforts are devoted to getting rid of their material restrictions and imparting them with abilities to carry various drugs.
Xiaoxuan Zhang +2 more
exaly +2 more sources
A Review of 3D-Printing of Microneedles
Pharmaceutics, 2022 Microneedles are micron-sized devices that are used for the transdermal administration of a wide range of active pharmaceutics substances with minimally invasive pain. In the past decade, various additive manufacturing technologies have been used for the
Salil Desai +2 more
exaly +3 more sources
Microneedles: Selected Applications for Pediatrics [PDF]
ChildrenMicroneedles are a pediatric-friendly drug delivery system that has attracted many novel research endeavors. The fact that it creates a tiny cavity in the epidermis, which can allow peptides, proteins, nucleotides, and other large-sized molecules to ...
Alexis A. Ayala, Hassan Almoazen
doaj +2 more sources
The Influence of Mask Modification on Microneedle Strength in Deep X-Ray Lithography [PDF]
MicromachinesHollow microneedle arrays of different shapes were prepared for blood collection and precise drug delivery. This microneedle array was investigated using shape modification and hole position optimization, and different approaches to increase the strength
Jie Wang, Yigui Li, Lin Du
doaj +2 more sources
Developing hierarchical microneedles for biomedical applications
Engineered Regeneration, 2023 As a new kind of microcarrier device, microneedles are featured by micrometer needle arrays with an overall size in the centimeter scale. Due to the needle shape and the micron size, microneedles can penetrate the skin without harming nerves and blood ...
Minhui Lu +3 more
doaj +1 more source
Polymeric Microneedles: An Emerging Paradigm for Advanced Biomedical Applications
Scientia Pharmaceutica, 2023 Microneedles are gaining popularity as a new paradigm in the area of transdermal drug delivery for biomedical and healthcare applications. Efficient drug delivery with minimal invasion is the prime advantage of microneedles.
Deepak Kulkarni +10 more
doaj +1 more source
Pharmaceutics, 2023 Microneedles are a patient-friendly technique for delivering drugs to the site of action in place of traditional oral and injectable administration.
Zhenzhen Qi +7 more
doaj +1 more source
Pharmaceutics, 2023 Hyaluronidase is clinically used in treating many skin diseases due to its good permeability-promoting effect, which may motivate the diffusion and absorption of drugs. To verify the penetration osmotic effect of hyaluronidase in microneedles, 55 nm-size
Xiaoqing Miao +3 more
doaj +1 more source
Microneedle, bio-microneedle and bio-inspired microneedle: A review [PDF]
Journal of Controlled Release, 2017 Microneedles (MNs) are micro-scale needles used for drug delivery and other targets. Micro-scale size endows them with many advantages over hypodermic needles, including painlessness, minimal invasiveness and convenient operation, but it may also lead to risk of mechanical failures, which should be prevented in the clinical applications of MNs.
Guojun, Ma, Chengwei, Wu
openaire +2 more sources