Results 1 to 10 of about 15,352 (268)
Transdermal Delivery of Drugs With Microneedles—Potential and Challenges [PDF]
Pharmaceutics, 2015 Transdermal drug delivery offers a number of advantages including improved patient compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect.
Kevin Ita
exaly +4 more sources
A Review of 3D-Printing of Microneedles
Pharmaceutics, 2022 Microneedles are micron-sized devices that are used for the transdermal administration of a wide range of active pharmaceutics substances with minimally invasive pain. In the past decade, various additive manufacturing technologies have been used for the
Salil Desai, Santosh Kumar Parupelli
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Polymeric Microneedles: An Emerging Paradigm for Advanced Biomedical Applications
Scientia Pharmaceutica, 2023 Microneedles are gaining popularity as a new paradigm in the area of transdermal drug delivery for biomedical and healthcare applications. Efficient drug delivery with minimal invasion is the prime advantage of microneedles.
Deepak Kulkarni +10 more
doaj +2 more sources
Gas-propelled microneedles for precision transdermal therapeutics [PDF]
Bioactive MaterialsTransdermal drug delivery is an appealing approach because it is easy to administer, bypasses first-pass metabolism, and utilizes an extensive surface area of the skin.
Zhicheng Xiao +9 more
doaj +2 more sources
Mechanical Properties and Fabrication of Bioinspired Cactus Spine Microneedles [PDF]
BiosensorsMicroneedle-based transdermal drug delivery enables painless and efficient drug administration but is limited by insufficient mechanical strength and high insertion forces.
Hongru Liu +4 more
doaj +2 more sources
Versatile Ice Microneedles for Transdermal Delivery of Diverse Actives
Advanced Science, 2021 Microneedles are regarded as an emerging and promising transdermal drug delivery strategy. Great efforts are devoted to getting rid of their material restrictions and imparting them with abilities to carry various drugs.
Xiaoxuan Zhang +2 more
exaly +2 more sources
Developing hierarchical microneedles for biomedical applications
Engineered Regeneration, 2023 As a new kind of microcarrier device, microneedles are featured by micrometer needle arrays with an overall size in the centimeter scale. Due to the needle shape and the micron size, microneedles can penetrate the skin without harming nerves and blood ...
Minhui Lu +3 more
doaj +1 more source
Microneedles in Action: Microneedling and Microneedles-Assisted Transdermal Delivery
Polymers, 2022 Human skin is a multilayered physiochemical barrier protecting the human body. The stratum corneum (SC) is the outermost keratinized layer of skin through which only molecules with less or equal to 500 Da (Dalton) in size can freely move through the skin.
Lim, Dong-Jin, Kim, Hong-Jun
openaire +2 more sources
Pharmaceutics, 2023 Microneedles are a patient-friendly technique for delivering drugs to the site of action in place of traditional oral and injectable administration.
Zhenzhen Qi +7 more
doaj +1 more source
Pharmaceutics, 2023 Hyaluronidase is clinically used in treating many skin diseases due to its good permeability-promoting effect, which may motivate the diffusion and absorption of drugs. To verify the penetration osmotic effect of hyaluronidase in microneedles, 55 nm-size
Xiaoqing Miao +3 more
doaj +1 more source