Results 11 to 20 of about 12,393 (293)
Coated microneedles for transdermal delivery [PDF]
Journal of Controlled Release, 2007 Coated microneedles have been shown to deliver proteins and DNA into the skin in a minimally invasive manner. However, detailed studies examining coating methods and their breadth of applicability are lacking.
Harvinder Singh Gill, Mark R Prausnitz
exaly +1 more source
Microneedles: Selected Applications for Pediatrics [PDF]
ChildrenMicroneedles are a pediatric-friendly drug delivery system that has attracted many novel research endeavors. The fact that it creates a tiny cavity in the epidermis, which can allow peptides, proteins, nucleotides, and other large-sized molecules to ...
Alexis A. Ayala, Hassan Almoazen
doaj +2 more sources
The Influence of Mask Modification on Microneedle Strength in Deep X-Ray Lithography [PDF]
MicromachinesHollow microneedle arrays of different shapes were prepared for blood collection and precise drug delivery. This microneedle array was investigated using shape modification and hole position optimization, and different approaches to increase the strength
Jie Wang, Yigui Li, Lin Du
doaj +2 more sources
Advances of Microneedles in Biomedical Applications
Molecules, 2021 A microneedle (MN) is a painless and minimally invasive drug delivery device initially developed in 1976. As microneedle technology evolves, microneedles with different shapes (cone and pyramid) and forms (solid, drug-coated, hollow, dissolvable and ...
Jie Xu +3 more
doaj +2 more sources
Microneedle Technology for Overcoming Biological Barriers: Advancing Biomacromolecular Delivery and Therapeutic Applications in Major Diseases [PDF]
ResearchBiomacromolecules are now widely employed in the therapy of major diseases such as tumors, infections, cardiovascular diseases, metabolic diseases, and autoimmune diseases.
Weishi Ye +12 more
doaj +2 more sources
Microneedles in Action: Microneedling and Microneedles-Assisted Transdermal Delivery
Polymers, 2022 Human skin is a multilayered physiochemical barrier protecting the human body. The stratum corneum (SC) is the outermost keratinized layer of skin through which only molecules with less or equal to 500 Da (Dalton) in size can freely move through the skin.
Lim, Dong-Jin, Kim, Hong-Jun
openaire +2 more sources
Pharmaceutics, 2023 Microneedles are a patient-friendly technique for delivering drugs to the site of action in place of traditional oral and injectable administration.
Zhenzhen Qi +7 more
doaj +1 more source
Microneedle, bio-microneedle and bio-inspired microneedle: A review [PDF]
Journal of Controlled Release, 2017 Microneedles (MNs) are micro-scale needles used for drug delivery and other targets. Micro-scale size endows them with many advantages over hypodermic needles, including painlessness, minimal invasiveness and convenient operation, but it may also lead to risk of mechanical failures, which should be prevented in the clinical applications of MNs.
Guojun, Ma, Chengwei, Wu
openaire +2 more sources
Pharmaceutics, 2023 Hyaluronidase is clinically used in treating many skin diseases due to its good permeability-promoting effect, which may motivate the diffusion and absorption of drugs. To verify the penetration osmotic effect of hyaluronidase in microneedles, 55 nm-size
Xiaoqing Miao +3 more
doaj +1 more source
Research progress in hydrogel microneedle
Cailiao gongcheng, 2023 Microneedles (MN) as a minimally invasive device consisting of a micro-raised array, can penetrate the cuticle to the epidermis and dermis, and which has the advantages of safety, painless, minimally invasive, self-administration and convenience.
LIU Guodong +5 more
doaj +1 more source