Revolutionizing diabetic wound healing: The power of microneedles
Diabetic wounds significantly affect patient quality of life. Microneedles are a promising treatment to accelerate wound healing owing to their high drug-loading capacity and efficient drug delivery; however, few studies to date have comprehensively ...
Chun Liang +9 more
doaj +1 more source
Mechanical properties and immunotherapeutic effects of dissolving microneedles with different drug loadings based on hyaluronic acid [PDF]
Improving vaccine immunity and reducing antigen usage are major challenges in the clinical application of vaccines. Microneedles have been proven to be painless, minimally invasive, highly efficient, and have good patient compliance.
Dazhi Wang +5 more
doaj +1 more source
Dissolving microneedles: Applications and growing therapeutic potential [PDF]
Microneedles are a rapidly developing method for the transdermal delivery of therapeutic compounds. All types of microneedles, whether solid, hollow, coated, or dissolving function by penetrating the stratum corneum layer of the skin producing a ...
Blackshields, Caroline +5 more
core +1 more source
Integrated O<sub>2</sub> and H<sub>2</sub> Gas Therapy via Microneedle-Assisted Photocatalytic Water Splitting for Accelerating Diabetic Full-Thickness Skin Wound Healing. [PDF]
A concept of integrated O2 and H2 gas therapy is achieved using a gas‐producing material. PMP nanoparticles, fabricated from platinum, MIL‐101(Fe)‐NH2, and phosphotungstic acid, are integrated into bilayer gelatin methacryloyl microneedles for transdermal delivery. These microneedles enable integrated O2 and H2 gas therapy and promote wound healing via
Chen Z +13 more
europepmc +2 more sources
Laser-based additive manufacturing methods have been rapidly developed in recent years and it is anticipated that this new generation of microfabrication tools will dominate the market in the near future. Three-dimensional (3D) microprinting based on two-
Philip D. Prewett +5 more
core +1 more source
Layer-Specific Dermal and Subcutaneous Delivery via Modular LNP-Hydrogel-Integrated Threaded Microneedles. [PDF]
Guided by spatial transcriptomics and clinical validation, a threaded microneedle platform enables precise layer‐specific delivery across the dermis and subcutaneous tissue. By addressing distinct pathogenic remodeling in different skin layers, this strategy coordinates compartment‐specific intervention, restores tissue architecture, and offers a ...
Xie F +14 more
europepmc +2 more sources
Knowledge about microneedles & attitudes towards microneedles administration, N = 1182.
Knowledge about microneedles & attitudes towards microneedles administration, N = 1182.
Mais Melhem (17014729) +6 more
core +1 more source
Microneedles from fish scale biopolymer [PDF]
This article reports on microneedles produced from biopolymer films extracted from fish scales of tilapia (Oreochromiss sp.) using micromolding technique.
Ololade Olatunji (7127834) +5 more
core +8 more sources
Electrochemical Microneedles: Innovative Instruments in Health Care
As a significant part of drug therapy, the mode of drug transport has attracted worldwide attention. Efficient drug delivery methods not only markedly improve the drug absorption rate, but also reduce the risk of infection.
Zhijun Liao, Qian Zhou, Bingbing Gao
doaj +1 more source
A BRIEF OVERVIEW ON MICRONEEDLES
Transdermal drug delivery carried out a promising carrier in the transport of drugs to get direct access across the skin deep into the systemic circulation.
A. V. S. Himabindu*, M. Manasa, N. Neeraja, M. J. L. Manasa Reddy, B. Umadevi, S. Umamaheswari, K. Padmalatha
core +1 more source

