Results 31 to 40 of about 15,352 (268)

Hard polymeric porous microneedles on stretchable substrate for transdermal drug delivery

open access: yesScientific Reports, 2022
Microneedles offer a convenient transdermal delivery route with potential for long term sustained release of drugs. However current microneedle technologies may not have the mechanical properties for reliable and stable penetration (e.g.
Aydin Sadeqi   +4 more
doaj   +1 more source

High fidelity replication of thermoplastic microneedles with open microfluidic channels [PDF]

open access: yes, 2017
Development of microneedles for unskilled and painless collection of blood or drug delivery addresses the quality of healthcare through early intervention at point-of-care.
Bilston, L ; https://orcid.org/   +22 more
core   +1 more source

Bioinspired Adhesive and Antibacterial Microneedles for Versatile Transdermal Drug Delivery

open access: yesResearch, 2020
Microneedles have attracted increasing interest among various medical fields due to their painless, noninvasive, and efficient way of drug delivery. However, practical applications of these microneedles in different epidermal locations and environments ...
Xiaoxuan Zhang   +4 more
doaj   +1 more source

Biodegradable double-network GelMA-ACNM hydrogel microneedles for transdermal drug delivery

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
As a minimally invasive drug delivery platform, microneedles (MNs) overcome many drawbacks of the conventional transdermal drug delivery systems, therefore are favorable in biomedical applications. Microneedles with a combined burst and sustained release
Wensheng Lin   +15 more
doaj   +1 more source

Universal Applicator for Digitally-Controlled Pressing Force and Impact Velocity Insertion of Microneedles into Skin

open access: yesPharmaceutics, 2018
Microneedle technologies have been developed for dermal drug and vaccine delivery, including hollow-, solid-, coated-, and dissolving microneedles. Microneedles have been made in many different geometries and of many different materials, all of which may
Mara Leone   +8 more
doaj   +1 more source

Microneedle-mediated drug delivery for cutaneous diseases

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Microneedles have garnered significant interest as transdermal drug delivery route owing to the advantages of nonselective loading capacity, minimal invasiveness, simple operation, and good biocompatibility.
Jian Chen   +6 more
doaj   +1 more source

Preparation and In Vitro Characterization of Microneedles Containing Inclusion Complexes Loaded with Progesterone

open access: yesPharmaceutics, 2023
Objective: In order to improve patient compliance and the ease of use during progesterone application, and to increase the clinical application of progesterone, progesterone was made into a microneedle. Methods: Progesterone complexes were prepared using
Hongji He   +6 more
doaj   +1 more source

Microneedles- A new paradigm in transdermal delivery of therapeutic agents [PDF]

open access: yesPharmaceutical Sciences Asia, 2022
Microneedles are a new mode of transdermal delivery system that delivers the drug through micron-size pathways caused by disruption of the epidermis. It is an effective procedure with an array of applications in dermatology and drug delivery with a low ...
Sayani Bhattacharyya   +1 more
doaj   +1 more source

Microneedles for in situ tissue regeneration

open access: yesMaterials Today Bio, 2023
Tissue injury is a common clinical problem, which may cause great burden on patients' life. It is important to develop functional scaffolds to promote tissue repair and regeneration.
Linyu Long   +5 more
doaj   +1 more source

Fabrication of Circular Obelisk-Type Multilayer Microneedles Using Micro-Milling and Spray Deposition

open access: yesFrontiers in Bioengineering and Biotechnology, 2018
In this study we present the fabrication of multilayer microneedles with circular obelisk and beveled-circular obelisk geometries, which have potential applications in implantable drug delivery devices.
Min Jung Kim   +7 more
doaj   +1 more source

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