Deferasirox Nanosuspension Loaded Dissolving Microneedles for Intradermal Delivery [PDF]
Pharmaceutics, 2022 Microneedles are minimally invasive systems that can deliver drugs intradermally without pain and bleeding and can advantageously replace the hypodermal needles and oral routes of delivery.
Muhammad Usman Minhas +2 more
exaly +7 more sources
Dissolving Microneedles for Rapid and Painless Local Anesthesia [PDF]
Pharmaceutics, 2020 Microneedles are emerging drug delivery methods for painless treatment. The current study tested dissolving microneedles containing lidocaine (Li-DMN) for use in local anesthesia.
Ui-Won Jung +2 more
exaly +6 more sources
Dissolving Microneedles for Intradermal Vaccination against Shigellosis [PDF]
Vaccines, 2019 Intradermal (ID) immunization is of increasing interest due to the easy accessibility and excellent immunogenic properties of the skin. Among ID immunization methods, dissolving microneedles (MNs) have appeared as an alternative to traditional hypodermic
Ivan Penuelas +2 more
exaly +7 more sources
Dissolving Polymer Microneedles for Transdermal Delivery of Insulin [PDF]
Frontiers in Pharmacology, 2021 It’s of great significance to develop insulin-loaded dissolving microneedles (MNs) which are fabricated with various methods and materials for transdermal delivery of insulin to effectively and efficiently treat diabetes.
Zhou Xinxin, Liu Libo
exaly +5 more sources
The Progress in the Application of Dissolving Microneedles in Biomedicine [PDF]
Polymers, 2023 In recent years, microneedle technology has been widely used for the transdermal delivery of substances, showing improvements in drug delivery effects with the advantages of minimally invasive, painless, and convenient operation. With the development of nano- and electrochemical technology, different types of microneedles are increasingly being used in
Fan Daidi
exaly +4 more sources
Mechanical Characterization of Dissolving Microneedles: Factors Affecting Physical Strength of Needles [PDF]
PharmaceuticsDissolving microneedles (MNs) are novel transdermal drug delivery systems that can be painlessly self-administered. This study investigated the effects of experimental conditions on the mechanical characterization of dissolving MNs for quality evaluation.
Hideyuki Sakoda +2 more
exaly +4 more sources
Fabrication and Evaluation of Rapidly Dissolving Microneedles Loaded with Organophosphorus Hydrolase for the Treatment of Transdermal Ethyl Paraoxon Poisoning [PDF]
PharmaceuticsBackground: Given the severe toxicity of organophosphates and the efficient catalytic hydrolysis of organophosphates by organophosphorus hydrolase (OPH) against them, a rapidly dissolving microneedle patch loaded with OPH offers a promising therapeutic ...
Fengqian Cui +4 more
doaj +2 more sources
Gels, 2023 Polymeric hydrogels are a complex class of materials with one common feature—the ability to form three-dimensional networks capable of imbibing large amounts of water or biological fluids without being dissolved, acting as self-sustained containers for ...
Maksims Babenko, Bana Shriky
exaly +3 more sources
Enhanced Skin Permeation and Controlled Release of β-Sitosterol Using Cubosomes Encrusted with Dissolving Microneedles for the Management of Alopecia [PDF]
Pharmaceuticals, 2023 The use of synthetic medication for treating alopecia is restricted because of systemic exposure and related negative effects. Beta-sitosterol (β-ST), a natural chemical, has lately been studied for its potential to promote hair development.
Kousalya Prabahar +3 more
doaj +2 more sources
Rapidly Separable Micropillar Integrated Dissolving Microneedles [PDF]
Pharmaceutics, 2020 Dissolving microneedle (DMN) patches were developed as efficient and patient-friendly transdermal delivery systems for biopharmaceuticals. However, recent studies have confirmed that the efficiency of DMNs to deliver biopharmaceuticals is highly reduced ...
Chung-ryong Jung +4 more
doaj +3 more sources