Results 31 to 40 of about 2,316 (200)

Design and Evaluation of Dissolving Microneedles for Enhanced Dermal Delivery of Propranolol Hydrochloride

Pharmaceutics, 2021
Oral propranolol hydrochloride has been the first-line treatment for infantile hemangioma (IH), whereas systemic exposure to propranolol has the potential of causing serious adverse reactions.
Jingjing He, Zichen Zhang, Xianzi Zheng, Lu Li, Jianping Qi, Wei Wu, Yi Lu   +6 more
doaj   +1 more source

Treatment of Hypertrophic Scars with Corticoid-Embedded Dissolving Microneedles

Journal of Burn Care & Research, 2022
Abstract Hypertrophic scarring (HTS) is frequently observed after deep dermal and full-thickness skin defects. Local drug delivery in HTS has been shown more effective compared to other (minimally) invasive treatments. Disadvantages being operator-dependency and non-uniform drug distribution.
Ignace De Decker, Anna Szabó, Henk Hoeksema, Marijn Speeckaert, Joris R Delanghe, Phillip Blondeel, Sandra Van Vlierberghe, Stan Monstrey, Karel E Y Claes   +8 more
openaire   +3 more sources

Technology update: dissolvable microneedle patches for vaccine delivery. [PDF]

Medical devices (Auckland, N.Z.), 2019
Despite vaccination representing one of the greatest advances of modern preventative medicine, there remain significant challenges in vaccine distribution, delivery and compliance. Dissolvable microarray patches or dissolving microneedles (DMN) have been proposed as an innovative vaccine delivery platform that could potentially revolutionize vaccine ...
Rodgers, Aoife M., Cordeiro, Ana Sara, Donnelly, Ryan F.   +2 more
openaire   +5 more sources

Fabrication Technology of Self-Dissolving Sodium Hyaluronate Gels Ultrafine Microneedles for Medical Applications with UV-Curing Gas-Permeable Mold

Gels
Microneedles are of great interest in diverse fields, including cosmetics, drug delivery systems, chromatography, and biological sensing for disease diagnosis.
Rio Yamagishi, Sayaka Miura, Kana Yabu, Mano Ando, Yuna Hachikubo, Yoshiyuki Yokoyama, Kaori Yasuda, Satoshi Takei   +7 more
doaj   +1 more source

Particle Size Effect of Curcumin Nanocrystals on Transdermal and Transfollicular Penetration by Hyaluronic Acid-Dissolving Microneedle Delivery

Pharmaceuticals, 2022
Microneedles are one promising penetration enhancement vehicle to overcome the stratum corneum skin barrier, which hampers the penetration of drug nanocrystals by transdermal delivery.
Hong Xiang, Sai Xu, Jingyuan Li, Shihui Pan, Xiaoqing Miao   +4 more
doaj   +1 more source

Rapid biodegradable microneedles with allergen reservoir for skin allergy test

Micro and Nano Systems Letters, 2020
With the increasing allergy cases worldwide, this study introduces a biodegradable microneedle system to facilitate allergy testing process. Dissolving microneedle provides a minimally invasive manner to go through skin barrier while avoiding needle ...
Le-Giang Tran, Woo-Tae Park
doaj   +1 more source

Design and Evaluation of Dissolvable Microneedles for Treating Atopic Dermatitis

Pharmaceutics, 2023
Atopic dermatitis (AD) is a chronic inflammatory skin disease caused predominantly by immune dysregulation. The global impact of AD continues to increase, making it not only a significant public health issue but also a risk factor for progression into other allergic phenotype disorders.
Noa Ben David, Yuval Richtman, Adi Gross, Ruba Ibrahim, Abraham Nyska, Yuval Ramot, Boaz Mizrahi   +6 more
openaire   +3 more sources

Design of scalable manufacturing process for the production of biodegradable polymeric microneedles for protein transdermal drug delivery

Разработка и регистрация лекарственных средств
Introduction. Dissolving polymeric microneedles are attractive drug delivery system especially for vaccine delivery. Still there are a lot of obstacles in developing scalable manufacturing process of them.Aim.
M. S. Zolotareva, V. V. Churikov, A. V. Panov, S. A. Kedik   +3 more
doaj   +1 more source

Universal Applicator for Digitally-Controlled Pressing Force and Impact Velocity Insertion of Microneedles into Skin

Pharmaceutics, 2018
Microneedle technologies have been developed for dermal drug and vaccine delivery, including hollow-, solid-, coated-, and dissolving microneedles. Microneedles have been made in many different geometries and of many different materials, all of which may
Mara Leone, Bart H. van Oorschot, M. Reza Nejadnik, Andrea Bocchino, Matteo Rosato, Gideon Kersten, Conor O’Mahony, Joke Bouwstra, Koen van der Maaden   +8 more
doaj   +1 more source

Functionalizing Micro‐to‐Mesoscopic Electrode Architectures for Regulating Electron Transfer Behaviors in Electrocatalysis

Advanced Functional Materials, EarlyView.
A systematic review is conducted to assess the influence of electrode architecture across micro‐ to mesoscopic length scales on electron‐transfer pathways in electrocatalysis. We discuss the structure‐activity relationships in electrocatalytic applications, including resource recovery and environmental remediation, and provide cost‐effective, efficient
Manshu Zhao, Jiaojiao Zhang, Shideng Yuan, Xinmeng Yu, Keming Wan, Xiaoguang Duan, Zhining Wang   +6 more
wiley   +1 more source