Results 21 to 30 of about 2,316 (200)
Vaccines, 2023 Respiratory syncytial virus (RSV) is one of the leading causes of bronchiolitis and pneumonia in children ages five years and below. Recent outbreaks of the virus have proven that RSV remains a severe burden on healthcare services.
Ipshita Menon +7 more
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Dissolving Microneedle Delivery of a Prophylactic HPV Vaccine
Biomacromolecules, 2022 Prophylactic vaccines capable of preventing human papillomavirus (HPV) infections are still inaccessible to a vast majority of the global population due to their high cost and challenges related to multiple administrations performed in a medical setting. In an effort to improve distribution and administration, we have developed dissolvable microneedles
Sayoni Ray +4 more
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Current Advances in Sustained Release Microneedles
Pharmaceutical Fronts, 2020 Microneedles have been extensively investigated for intradermal delivery of drugs and vaccines due to advantages including high skin delivery efficiency, improved patient compliance, and potential for self-administration.
Guangsheng Du, Xun Sun
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Viruses, 2022 Resistant bacteria prevail in most chronic skin wounds and other biofilm-related topical skin infections. Bacteriophages (phages) have proven their antimicrobial effectiveness for treating different antibiotic-resistant and multidrug-resistant bacterial ...
Sanna Sillankorva +3 more
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Bioimaging of Dissolvable Microneedle Arrays: Challenges and Opportunities
Research, 2022 The emergence of microneedle arrays (MNAs) as a novel, simple, and minimally invasive administration approach largely addresses the challenges of traditional drug delivery. In particular, the dissolvable MNAs act as a promising, multifarious, and well-controlled platform for micro-nanotransport in medical research and cosmetic formulation applications.
Yanni Wang +9 more
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Dissolving polymer microneedle patches for influenza vaccination [PDF]
Nature Medicine, 2010 Influenza prophylaxis would benefit from a vaccination method enabling simplified logistics and improved immunogenicity without the dangers posed by hypodermic needles. Here we introduce dissolving microneedle patches for influenza vaccination using a simple patch-based system that targets delivery to skin's antigen-presenting cells.
Sean P, Sullivan +9 more
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Dissolving microneedles: Applications and growing therapeutic potential
Journal of Controlled Release, 2022 Microneedles are a rapidly developing method for the transdermal delivery of therapeutic compounds. All types of microneedles, whether solid, hollow, coated, or dissolving function by penetrating the stratum corneum layer of the skin producing a microchannel through which therapeutic agents may be delivered. To date, coated and hollow microneedles have
Sartawi, Ziad +2 more
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Acta Pharmaceutica Sinica B, 2018 Dissolving microneedles carried drug molecules can effectively penetrate the stratum corneum of skin to improve the transdermal drug delivery. The traditional Chinese medicine acupuncture is based on the needle stimulation at a specific location ...
Qian Zhang +9 more
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Dermatology and Therapy, 2019 Introduction Keloids are a prevalent chronic skin disorder with significant psychosocial morbidity. Intralesional corticosteroid injections are the first-line treatment but are painful and require repeated injections by medical professionals.
Colin W. X. Tan +5 more
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Transdermal Delivery of Drugs with Microneedles—Potential and Challenges
Pharmaceutics, 2015 Transdermal drug delivery offers a number of advantages including improved patient compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect.
Kevin Ita
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