Results 241 to 250 of about 999,964 (314)

Advances in Tetrahedral Framework Nucleic Acids (tFNAs) for Lung Injury Repair: Mechanisms, Therapeutic Applications, and Future Directions. [PDF]

Int J Nanomedicine
Song J, Chen X, Hou Q, Zhao P, Zu X.
europepmc   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source

Evaluation and forecasting of siRNA delivery technologies: An analysis of hierarchical decision model based on patent data. [PDF]

Mol Ther Nucleic Acids
Chen S, Peng Y, Yan D, Lyu L, Scherngell T, Hu Y.   +5 more
europepmc   +1 more source

Engagement Patterns with an AI Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, Accepted Article.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed‐methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source

Role of Extracellular Vesicles in Skin Barrier Repair: Applications in Atopic Dermatitis and Chronic Wounds. [PDF]

Int J Nanomedicine
Khoo L, Chin YZ, Law JX.
europepmc   +1 more source

Understanding the burden of orofacial involvement and patient treatment preferences in systemic sclerosis: results from a large international survey

Arthritis Care &Research, Accepted Article.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc), yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprising 38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni, Lee Shapiro, Deana Gibbs, Zsuzsanna H. McMahan, Michael Hughes   +4 more
wiley   +1 more source

Nanotechnology based topical drug delivery systems for psoriasis addressing current strategies clinical progress and manufacturing challenges. [PDF]

Discov Nano
Bhoyar S, Pethe A.
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Advanced Sensing and Delivery Technologies for Nose-to-Brain Administration: From Nanocarriers to Sensor-Integrated Organ-on-Chips. [PDF]

Sensors (Basel)
Liu X, Chen R, Wu F, Yu B, Zhou G, Hu S, Zhang H, Wang P, Xu B, Zhuang L.   +9 more
europepmc   +1 more source